SCHEMBL5309809

SCHEMBL5309809

Nc1cc(N2CCCC2)nc(N)[n+]1[O-]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 7/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
CRHBP P24387 1/20 0.45
CRHR2 Q13324 1/20 0.45
NUDT1 P36639 3/20 0.42
LMNA P02545 2/20 0.41
TSHR P16473 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP1A2 P05177 1/20 0.41
HSD17B10 Q99714 2/20 0.40
CASP1 P29466 2/20 0.40
USP2 O75604 1/20 0.40
HTT P42858 1/20 0.40
CASP4 P49662 1/20 0.40
CASP5 P51878 1/20 0.40
HTR2A P28223 1/20 0.39
HTR6 P50406 1/20 0.39
CHRM3 P20309 1/20 0.39
PDE4A P27815 1/20 0.39
PDE4B Q07343 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Minoxidil SCHEMBL29698 0.98 SMN1; SMN2 (0.47) HRH4SMN1; SMN2CRHBPCRHR2NUDT1
Minoxidil SCHEMBL638820 0.98 SMN1; SMN2 (0.47) HRH4SMN1; SMN2CRHBPCRHR2NUDT1
Minoxidil SCHEMBL8860979 0.98 SMN1; SMN2 (0.47) HRH4SMN1; SMN2CRHBPCRHR2NUDT1
Minoxidil SCHEMBL29365549 0.98 SMN1; SMN2 (0.47) HRH4SMN1; SMN2CRHBPCRHR2NUDT1
Minoxidil SCHEMBL6242048 0.97 SMN1; SMN2 (0.46) HRH4SMN1; SMN2CRHBPCRHR2NUDT1
Minoxidil SCHEMBL3137104 0.97 SMN1; SMN2 (0.46) HRH4SMN1; SMN2CRHBPCRHR2NUDT1
Minoxidil SCHEMBL8080441 0.97 SMN1; SMN2 (0.46) HRH4SMN1; SMN2CRHBPCRHR2NUDT1
Minoxidil SCHEMBL7634414 0.97 SMN1; SMN2 (0.46) HRH4SMN1; SMN2CRHBPCRHR2NUDT1
Minoxidil SCHEMBL5080820 0.97 SMN1; SMN2 (0.46) HRH4SMN1; SMN2CRHBPCRHR2NUDT1
Minoxidil SCHEMBL22189162 0.91 SMN1; SMN2 (0.42) HRH4SMN1; SMN2CRHBPCRHR2NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120131459-A Anti-hair loss essence and preparation method thereof 广东凯乐生物技术有限公司 2025-06-13 CN claimed
CN-120131597-A Alopecia preventing composition and application thereof 广东凯乐生物技术有限公司 2025-06-13 CN claimed
WO-2025110928-A1 COMPOUNDS FOR TREATMENT OF POLYCYSTIC KIDNEY DISEASE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-05-30 WO claimed
CN-118480007-B Synthesis process of comparable drops 华泰民康(沈阳)科技有限公司 2024-10-18 CN claimed
CN-118480007-A Synthesis process of comparable drops 华泰民康(沈阳)科技有限公司 2024-08-13 CN claimed
US-10016351-B2 Composition for promoting hair growth or preventing hair loss NEOPHARM CO., LTD. (KR) 2018-07-10 US claimed
CN-104955460-B Emulsification composition 富士胶片株式会社 2018-06-19 CN claimed
US-20170239164-A1 COMPOSITION FOR PROMOTING HAIR GROWTH OR PREVENTING HAIR LOSS NEOPHARM CO., LTD. (KR) 2017-08-24 US claimed
CN-105658204-A Method for physically encapsulating, in hydrogel particle, liposome containing active ingredient, and cosmetic composition containing same 华斯泰株式会社 2016-06-08 CN claimed
WO-2007046577-A1 EXTERNAL COMPOSITION FOR HAIR GROWTH AMOREPACIFIC CORPORATION (KR) 2007-04-26 WO claimed
CN-120131459-B Anti-hair loss essence and preparation method thereof 广东凯乐生物技术有限公司 2026-01-16 CN disclosed
CN-120131597-B Alopecia preventing composition and application thereof 广东凯乐生物技术有限公司 2025-09-05 CN disclosed
CN-120131459-A Anti-hair loss essence and preparation method thereof 广东凯乐生物技术有限公司 2025-06-13 CN disclosed
CN-120131597-A Alopecia preventing composition and application thereof 广东凯乐生物技术有限公司 2025-06-13 CN disclosed
CN-120131597-A Alopecia preventing composition and application thereof 广东凯乐生物技术有限公司 2025-06-13 CN disclosed
EP-0187854-A4 SUBSTITUTED PYRIMIDINE OXIDES USEFUL FOR HAIR GROWTH PROMOTION. BAZZANO GAIL S 1987-01-22 EP disclosed
EP-0187854-A1 SUBSTITUTED PYRIMIDINE OXIDES USEFUL FOR HAIR GROWTH PROMOTION BAZZANO, Gail S (US) 1986-07-23 EP disclosed
WO-1986000616-A1 SUBSTITUTED PYRIMIDINE OXIDES USEFUL FOR HAIR GROWTH PROMOTION BAZZANO GAIL SANSONE 1986-01-30 WO disclosed
US-4393065-A INCREASED PRODUCTIVITY OF BY-PRODUCTS BY INCLUSION OF PYRIMIDINE COMPOUNDS THE UPJOHN COMPANY (US) 1983-07-12 US disclosed
EP-0042669-A2 Compounds and compositions for use in animal feeds THE UPJOHN COMPANY (US) 1981-12-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170239164-A1 COMPOSITION FOR PROMOTING HAIR GROWTH OR PREVENTING HAIR LOSS FGF1, CUTA, NGF HRH4 4355/4885SMN1; SMN2 3796/4885CRHBP 842/4885
US-10016351-B2 Composition for promoting hair growth or preventing hair loss FGF1, CUTA, NGF HRH4 4355/4885SMN1; SMN2 3796/4885CRHBP 842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.