Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 5/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310783 | 0.89 | SCD (0.46) | SCDGABRA1 | |
| SCHEMBL5312928 | 0.84 | SCD (0.50) | SCDGABRA1 | |
| SCHEMBL5307870 | 0.82 | ASPH (0.43) | SCDALDH1A1STING1 | |
| SCHEMBL5315830 | 0.73 | ASPH (0.48) | — | |
| SCHEMBL5312220 | 0.72 | SCD (0.47) | SCDGABRA1 | |
| SCHEMBL5376686 | 0.71 | NPC1 (0.39) | SCDNPC1ALDH1A1STING1 | |
| SCHEMBL5310095 | 0.70 | KCNMA1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13932843 | 0.70 | MLYCD (0.48) | HDAC4SMN1; SMN2ALDH1A1HSD17B10LMNA | |
| SCHEMBL5314293 | 0.69 | ADORA2A (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5313162 | 0.69 | CNR2 (0.48) | SCDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044085-A2 | HETEROARYL COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-19 | — | — | WO | disclosed |