Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330886 | 0.88 | LMNA (0.34) | MITFALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL1594419 | 0.83 | MITF (0.52) | MITFALDH1A1KMT2AMEN1GAA | |
| Hydrochloric Acid SCHEMBL5741754 | 0.82 | MITF (0.51) | MITFALDH1A1KMT2AMEN1GAA | |
| SCHEMBL3287960 | 0.81 | ALDH1A1 (0.41) | MITFALDH1A1KMT2APKML3MBTL1 | |
| Lithium SCHEMBL30668131 | 0.80 | ALDH1A1 (0.40) | MITFALDH1A1KMT2APKML3MBTL1 | |
| SCHEMBL30668083 | 0.80 | ALDH1A1 (0.40) | MITFALDH1A1KMT2APKMSMN1; SMN2 | |
| SCHEMBL9385677 | 0.80 | ALDH1A1 (0.40) | MITFALDH1A1KMT2AGAAPKM | |
| SCHEMBL5333313 | 0.79 | P2RY12 (0.37) | MITFNPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL14003294 | 0.78 | P2RY12 (0.40) | MITFNPSR1KMT2AMEN1MAPT | |
| SCHEMBL9385579 | 0.77 | ALDH1A1 (0.36) | MITFALDH1A1KMT2AGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230310640-A1 | PYRROLOBENZODIAZEPINE DERIVATIVE AND LIGAND-LINKER CONJUGATE THEREOF | LEGOCHEM BIOSCIENCES, INC. (KR) | 2023-10-05 | — | — | US | disclosed |
| WO-2023149487-A1 | METHOD FOR PRODUCING PYRROLE-IMIDAZOLE POLYAMIDE | 国立大学法人千葉大学 | 2023-08-10 | — | — | WO | disclosed |
| US-20070265240-A1 | Sequence Selective Pyrrole and Imidazole Polyamide Metallocomplexes | UNIVERSITY OF WESTERN SYDNEY (AU) | 2007-11-15 | — | — | US | disclosed |
| WO-2007045096-A1 | OLIGOHETEROAROMATIC LUMINISCENT ASSEMBLIES AS HIGH-AFFINITY DNA SEQUENCE-DIRECTED LIGANDS | UNIVERSITY OF SASKATCHEWAN (CA) | 2007-04-26 | — | — | WO | disclosed |
| CN-1211371-C | Single imidazole/multiamine acylamide kind compound and its synthesis method and use | UNIV TSINGHUA (CN) | 2005-07-20 | — | — | CN | disclosed |
| CN-1475483-A | Single imidazole/multiamine acylamide kind compound and its synthesis method and use | 清华大学 | 2004-02-18 | — | — | CN | disclosed |
| WO-2003020877-A2 | STAINING AND SORTING GENOMES AND CHROMOSOMES USING SEQUENCE-SPECIFIC POLYAMIDES | PHARMACIA CORPORATION (US) | 2003-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265240-A1 | Sequence Selective Pyrrole and Imidazole Polyamide Metallocomplexes | POLRMT, MPI, PPIF | MITF 740/4885NPSR1 1934/4885ALDH1A1 3611/4885 |
| US-20230310640-A1 | PYRROLOBENZODIAZEPINE DERIVATIVE AND LIGAND-LINKER CONJUGATE THEREOF | BCR, PDCD1LG2, PRLHR | MITF 3719/4885NPSR1 153/4885ALDH1A1 1636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.