SCHEMBL5313816

SCHEMBL5313816

CC(NC(=O)CCl)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MME P08473 2/20 0.47
ACE P12821 1/20 0.47
CPA1 P15085 1/20 0.47
ACE2 Q9BYF1 1/20 0.47
SMN1; SMN2 Q16637 6/20 0.46
ALDH1A1 P00352 7/20 0.44
LMNA P02545 3/20 0.44
MAPT P10636 1/20 0.44
FAAH O00519 3/20 0.43
KDM4E B2RXH2 2/20 0.42
TSHR P16473 2/20 0.41
SLC6A5 Q9Y345 1/20 0.41
HTT P42858 3/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
RAB9A P51151 1/20 0.38
HSD17B10 Q99714 1/20 0.38
NCOA1 Q15788 1/20 0.38
NCOA3 Q9Y6Q9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16892770 1.00 MME (0.47) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL6366655 1.00 MME (0.47) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL18010311 0.92 MME (0.50) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL10960732 0.79 FAAH (0.54) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL1476947 0.78 SMN1; SMN2 (0.47) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL10076082 0.78 ALDH1A1 (0.50) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL964581 0.78 SMN1; SMN2 (0.47) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL4811341 0.78 SMN1; SMN2 (0.47) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL4811735 0.78 SMN1; SMN2 (0.47) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL6309640 0.78 SMN1; SMN2 (0.47) MMEACECPA1ACE2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119529814-A Self-generated composite acid fracturing fluid without preparation and application thereof 中国石油天然气股份有限公司 2025-02-28 CN claimed
CN-109908361-B Targeting polypeptide-cucurbituril supramolecular assembly based on regulation and control of microtubule aggregation and preparation method and application thereof 南开大学 2020-07-31 CN claimed
US-12565517-B2 Cyclic peptide having CTLA-4 inhibitory activity and use thereof GENEFRONTIER CORPORATION (JP) 2026-03-03 US disclosed
CN-119355279-B Method for enriching protein containing reduced sulfhydryl based on chemical covalent bonding technology 国科大杭州高等研究院 2025-03-28 CN disclosed
CN-119529814-A Self-generated composite acid fracturing fluid without preparation and application thereof 中国石油天然气股份有限公司 2025-02-28 CN disclosed
CN-119355279-A Method for enriching protein containing reduced sulfhydryl based on chemical covalent bonding technology 国科大杭州高等研究院 2025-01-24 CN disclosed
EP-4043076-B1 CYCLIC PEPTIDE HAVING CTLA-4 INHIBITORY ACTIVITY AND USE THEREOF GENEFRONTIER CORP (JP) 2024-06-26 EP disclosed
US-20240092836-A1 CYCLIC PEPTIDE HAVING CTLA-4 INHIBITORY ACTIVITY AND USE THEREOF GENEFRONTIER CORPORATION (JP) 2024-03-21 US disclosed
CN-116888138-A Radiopharmaceutical conjugate compositions and uses thereof 瑞择生物公司 2023-10-13 CN disclosed
EP-4043076-A1 CYCLIC PEPTIDE HAVING CTLA-4 INHIBITORY ACTIVITY AND USE THEREOF GeneFrontier Corporation (JP) 2022-08-17 EP disclosed
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
WO-2021070696-A1 CYCLIC PEPTIDE HAVING CTLA-4 INHIBITORY ACTIVITY AND USE THEREOF ジーンフロンティア株式会社 2021-04-15 WO disclosed
CN-109908361-B Targeting polypeptide-cucurbituril supramolecular assembly based on regulation and control of microtubule aggregation and preparation method and application thereof 南开大学 2020-07-31 CN disclosed
US-20160083516-A1 CROSSLINKED POLY-DEPSIPEPTIDE COPOLYMERS AND METHODS OF MAKING THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-03-24 US disclosed
US-20160083516-A1 CROSSLINKED POLY-DEPSIPEPTIDE COPOLYMERS AND METHODS OF MAKING THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-03-24 US disclosed
US-20160083516-A1 CROSSLINKED POLY-DEPSIPEPTIDE COPOLYMERS AND METHODS OF MAKING THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-03-24 US disclosed
WO-2007074390-A2 PROCESS FOR PREPARING RHODANINE-3-ACETIC ACID: A KEY INTERMEDIATED OF EPALRESTAT KHAMAR BAKULESH MAFATLAL (IN) 2007-07-05 WO disclosed
US-4055663-A Halogenated acylamino acids as fungicides NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1977-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240092836-A1 CYCLIC PEPTIDE HAVING CTLA-4 INHIBITORY ACTIVITY AND USE THEREOF CXCL10, CXCR3, CXCR6 MME 1528/4885ACE 3306/4885CPA1 279/4885
US-12565517-B2 Cyclic peptide having CTLA-4 inhibitory activity and use thereof CXCL10, MLX, MICA MME 1493/4885ACE 3534/4885CPA1 497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.