Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17350738 | 0.98 | NFKB1 (0.32) | DNM1SIGMAR1NFKB1 | |
| Hydrochloric Acid SCHEMBL28449838 | 0.96 | DNM1 (0.32) | DNM1SIGMAR1NFKB1 | |
| Bromide SCHEMBL530788 | 0.93 | KEAP1 (0.31) | — | |
| SCHEMBL27695967 | 0.91 | KEAP1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL28046668 | 0.89 | KEAP1 (0.31) | — | |
| SCHEMBL12220168 | 0.89 | — | — | |
| SCHEMBL12220208 | 0.86 | — | — | |
| SCHEMBL12220182 | 0.86 | — | — | |
| SCHEMBL12220163 | 0.86 | — | — | |
| SCHEMBL12220188 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105315993-B | The preparation method of a kind of Ionic Liquid Modified carbon quantum dot | 中国科学院兰州化学物理研究所 | 2018-06-08 | — | — | CN | claimed |
| CN-105315993-B | The preparation method of a kind of Ionic Liquid Modified carbon quantum dot | 中国科学院兰州化学物理研究所 | 2018-06-08 | — | — | CN | disclosed |
| EP-2415741-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120010417-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010417-A1 | METHOD FOR PRODUCING ALCOHOL COMPOUND | ADH1A, ADH1C, ADH5 | SIGMAR1 1959/4885DNM1 2467/4885NFKB1 2604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.