Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317775 | 0.84 | LMNA (0.34) | — | |
| SCHEMBL13754055 | 0.82 | PDE2A (0.37) | — | |
| SCHEMBL5314215 | 0.76 | UGT2B7 (0.40) | — | |
| SCHEMBL28381315 | 0.75 | CHRNA7 (0.43) | CHRNA7 | |
| SCHEMBL25553550 | 0.74 | CHRNA7 (0.37) | CHRNA7 | |
| SCHEMBL5313188 | 0.73 | ESR1 (0.39) | — | |
| SCHEMBL13754053 | 0.70 | ALDH1A1 (0.35) | — | |
| SCHEMBL8977935 | 0.68 | TGM2 (0.38) | CHRNA7 | |
| SCHEMBL28701229 | 0.67 | ALDH1A1 (0.41) | — | |
| SCHEMBL4635846 | 0.66 | CHRNA7 (0.37) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314246-B2 | Catalytic reactions involving alkenes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-11-20 | — | — | US | disclosed |
| US-20090216025-A1 | Catalytic reactions involving alkenes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-08-27 | — | — | US | disclosed |
| WO-2007027752-A1 | CATALYTIC REACTIONS INVOLVING ALKENES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090216025-A1 | Catalytic reactions involving alkenes | ADH5, ADH1C, ADH1A | CHRNA7 2641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.