⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026427 | 0.94 | — | — | |
| SCHEMBL1584170 | 0.92 | CES2 (0.50) | — | |
| SCHEMBL3645869 | 0.88 | — | — | |
| SCHEMBL14488967 | 0.80 | HTT (0.33) | — | |
| SCHEMBL6925922 | 0.80 | AAK1 (0.35) | — | |
| SCHEMBL2201861 | 0.79 | SMN1; SMN2 (0.54) | — | |
| SCHEMBL12174861 | 0.79 | HTT (0.31) | — | |
| SCHEMBL12174860 | 0.79 | LMNA (0.43) | — | |
| SCHEMBL17895344 | 0.77 | PIK3CD (0.32) | — | |
| SCHEMBL2056468 | 0.77 | GABRA1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3638227-A1 | SPIROCYCLIC INDOLINES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2020-04-22 | — | — | EP | disclosed |
| WO-2018229079-A1 | SPIROCYCLIC INDOLINES AS IL-17 MODULATORS | UCB BIOPHARMA SPRL (BE) | 2018-12-20 | — | — | WO | disclosed |
| WO-2007146695-A1 | ACYCLIC OXIMYL HEPATITIS C PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| US-4431665-A | Acylated laidlomycin derivatives | SYNTEX (U.S.A.) INC. (US) | 1984-02-14 | — | — | US | disclosed |
| EP-0024189-B1 | ACYLATED LAIDLOMYCIN DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS | SYNTEX (U.S.A.) INC. (US) | 1983-03-02 | — | — | EP | disclosed |
| EP-0024189-A1 | Acylated laidlomycin derivatives, their preparation and compositions | SYNTEX (U.S.A.) INC. (US) | 1981-02-25 | — | — | EP | disclosed |