Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 4/20 | 0.43 |
| ▸ | BCR | P11274 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 2/20 | 0.40 |
| ▸ | FLT4 | P35916 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14466977 | 0.86 | TRPV1 (0.61) | SMOTRPV1IMPDH2KDRCDC7 | |
| SCHEMBL5318416 | 0.86 | TNIK (0.60) | IMPDH2ROCK2TNIKKDRFLT1 | |
| SCHEMBL5317585 | 0.85 | KDM4E (0.46) | SMOTRPV1IMPDH2ROCK2TNIK | |
| SCHEMBL5335613 | 0.85 | CDC7 (0.58) | TRPV1IMPDH2ROCK2TNIKKDR | |
| SCHEMBL5336680 | 0.82 | IMPDH2 (0.59) | IMPDH2KDRFLT1FLT4 | |
| SCHEMBL5316809 | 0.82 | NOS1 (0.48) | TRPV1IMPDH2ROCK2TNIKKDR | |
| SCHEMBL5333205 | 0.82 | IMPDH2 (0.53) | IMPDH2ROCK2TNIKKDRCDC7 | |
| SCHEMBL5336433 | 0.82 | MKNK1 (0.51) | TRPV1IMPDH2ROCK2TNIKKDR | |
| SCHEMBL5333863 | 0.82 | VCP (0.58) | IMPDH2ROCK2TNIKKDRCDC7 | |
| SCHEMBL5343891 | 0.82 | VCP (0.58) | IMPDH2ROCK2TNIKKDRCDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |