Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL717757 | 0.87 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| Iodide SCHEMBL7715452 | 0.78 | MEN1 (0.47) | MEN1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6254665 | 0.76 | LMNA (0.53) | CYP1A2CYP2D6KMT2ASMN1; SMN2LMNA | |
| SCHEMBL6740564 | 0.75 | KMT2A (0.51) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL841362 | 0.72 | KMT2A (0.49) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL15716450 | 0.72 | GAA (0.46) | MEN1CYP1A2CYP2D6KMT2ASMN1; SMN2 | |
| SCHEMBL6567345 | 0.72 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL9505332 | 0.71 | ALDH1A1 (0.66) | SMN1; SMN2EPHX1HTT | |
| SCHEMBL27779846 | 0.71 | SIGMAR1 (0.43) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL29291234 | 0.71 | CTSD (0.51) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007080109-A1 | SUBSTITUDED BENZYLOXY-PHENYLMETHYLUREA DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-19 | — | — | WO | disclosed |
| WO-2007080109-A1 | SUBSTITUDED BENZYLOXY-PHENYLMETHYLUREA DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-19 | — | — | WO | disclosed |