Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19066161 | 0.85 | CA2 (0.55) | ALDH1A1POLBHSD11B1SMN1; SMN2MEN1 | |
| SCHEMBL5253103 | 0.82 | ALDH1A1 (0.34) | ALDH1A1POLBHSD11B1SMN1; SMN2GAA | |
| SCHEMBL7694247 | 0.77 | ALDH1A1 (0.36) | ALDH1A1POLBHSD11B1MAPTHPGD | |
| SCHEMBL1114107 | 0.76 | ALDH1A1 (0.39) | ALDH1A1POLBSMN1; SMN2MAPTHPGD | |
| SCHEMBL2483464 | 0.76 | ALDH1A1 (0.39) | ALDH1A1POLBSMN1; SMN2MAPTHPGD | |
| SCHEMBL25352240 | 0.74 | ALDH1A1 (0.52) | ALDH1A1POLBHSD11B1SMN1; SMN2MEN1 | |
| SCHEMBL15414871 | 0.74 | ALDH1A1 (0.38) | ALDH1A1POLBSMN1; SMN2MAPTHTT | |
| SCHEMBL10594339 | 0.74 | ALDH1A1 (0.38) | ALDH1A1POLBMAPTHPGDMMP1 | |
| Water SCHEMBL11439691 | 0.74 | ALDH1A1 (0.38) | ALDH1A1POLBMAPTHPGDMMP1 | |
| SCHEMBL5597410 | 0.74 | ALDH1A1 (0.38) | ALDH1A1POLBSMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666734-A | Honokiol derivative and preparation method and application thereof | 上海植瑞新成医药科技有限公司 | 2024-09-20 | — | — | CN | disclosed |
| WO-2007106797-A2 | A METHOD OF USE FOR SUBSTITUTED DIPIPERIDINE CCR2 ANTAGONISTS | JANSSEN PHARMACEUTICA, NV (BE) | 2007-09-20 | — | — | WO | disclosed |
| US-20070219245-A1 | METHOD OF USE FOR SUBSTITUTED DIPIPERIDINE CCR2 ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-09-20 | — | — | US | disclosed |
| US-20060069123-A1 | Substituted dipiperidine CCR2 antagonists | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069123-A1 | Substituted dipiperidine CCR2 antagonists | CCR2, CCR1, CCR5 | ALDH1A1 934/4885POLB 2222/4885HSD11B1 785/4885 |
| US-20070219245-A1 | METHOD OF USE FOR SUBSTITUTED DIPIPERIDINE CCR2 ANTAGONISTS | CCR2, CCR5, CCR1 | ALDH1A1 995/4885POLB 1994/4885HSD11B1 479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.