Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533437 | 0.84 | CYTH2 (0.49) | ALDH1A1GAAKMT2AMAPTMEN1 | |
| SCHEMBL533017 | 0.84 | FFAR4 (0.55) | L3MBTL1ALDH1A1GAAKMT2AMAPT | |
| SCHEMBL533059 | 0.84 | MEN1 (0.55) | GFERL3MBTL1ALDH1A1GAAKMT2A | |
| SCHEMBL533666 | 0.82 | FFAR4 (0.56) | L3MBTL1ALDH1A1GAAKMT2AMAPT | |
| SCHEMBL533055 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KMT2AMAPTMEN1POLB | |
| SCHEMBL532880 | 0.82 | FFAR4 (0.56) | L3MBTL1ALDH1A1GAAKMT2AMAPT | |
| SCHEMBL532776 | 0.82 | FFAR4 (0.54) | L3MBTL1ALDH1A1GAAKMT2AMAPT | |
| SCHEMBL533091 | 0.80 | BRPF1 (0.52) | ALDH1A1GAAKMT2AMAPTMEN1 | |
| SCHEMBL532953 | 0.80 | FFAR4 (0.59) | ALDH1A1KMT2AMAPTMEN1PKM | |
| SCHEMBL534077 | 0.80 | TSHR (0.47) | L3MBTL1ALDH1A1GAAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415760-A2 | CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2012-02-08 | — | — | EP | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |