SCHEMBL5320429

SCHEMBL5320429

O=CCc1ccc(S(=O)(=O)c2ccc(Cl)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.64
CYP3A4 P08684 1/20 0.64
MAPK1 P28482 1/20 0.64
KMT2A Q03164 5/20 0.53
MEN1 O00255 4/20 0.53
BCHE P06276 1/20 0.49
ACHE P22303 1/20 0.49
KDM4E B2RXH2 2/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CA1 P00915 4/20 0.43
CA2 P00918 4/20 0.43
CA12 O43570 3/20 0.43
CA4 P22748 3/20 0.43
CA9 Q16790 3/20 0.43
CA3 P07451 2/20 0.43
CA6 P23280 2/20 0.43
CA5A P35218 2/20 0.43
CA7 P43166 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL453913 0.85 IDO1 (0.48) ALDH1A1KMT2AMEN1HSD17B10
SCHEMBL6224571 0.82 HTR6 (0.58) ALDH1A1BCHEACHECA1CA2
SCHEMBL22742 0.80 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1KMT2AMEN1
SCHEMBL2122579 0.80 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1KMT2AMEN1
SCHEMBL9313173 0.80 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1KMT2AMEN1
SCHEMBL4328031 0.80 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1KMT2AMEN1
SCHEMBL4391356 0.79 MAOB (0.48) ALDH1A1KMT2AMEN1HSD17B10
SCHEMBL9245177 0.78 NAMPT (0.45) ALDH1A1CYP3A4KMT2AMEN1CA1
SCHEMBL5325616 0.78 VCAM1 (0.42) ALDH1A1CYP3A4MAPK1KMT2APOLB
SCHEMBL16713293 0.78 ALDH1A1 (0.94) ALDH1A1CYP3A4MAPK1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007114916-A2 ARYLBENZYLPIPERIDINE COMPOUNDS H. LUNDBECK A/S (DK) 2007-10-11 WO disclosed