Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 8/20 | 0.57 |
| ▸ | KDR | P35968 | 11/20 | 0.56 |
| ▸ | FLT1 | P17948 | 9/20 | 0.56 |
| ▸ | FLT4 | P35916 | 9/20 | 0.56 |
| ▸ | VCP | P55072 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316977 | 0.89 | VCP (0.55) | IMPDH2KDRFLT1FLT4VCP | |
| SCHEMBL5316833 | 0.83 | IMPDH2 (0.54) | IMPDH2KDRFLT1FLT4VCP | |
| SCHEMBL5319673 | 0.80 | PIK3CG (0.59) | IMPDH2KDRFLT1FLT4 | |
| SCHEMBL14466975 | 0.80 | KDR (0.60) | IMPDH2KDRFLT1FLT4VCP | |
| SCHEMBL5319793 | 0.75 | IMPDH2 (0.60) | IMPDH2KDRFLT1FLT4VCP | |
| SCHEMBL5318419 | 0.74 | KDR (0.56) | IMPDH2KDRFLT1FLT4VCP | |
| Gw549390X SCHEMBL3295009 | 0.73 | KDR (1.00) | IMPDH2KDRFLT1FLT4VCP | |
| SCHEMBL5318202 | 0.73 | KDR (0.61) | IMPDH2KDRFLT1FLT4VCP | |
| SCHEMBL5319635 | 0.73 | VCP (0.52) | IMPDH2KDRFLT1FLT4VCP | |
| SCHEMBL5340017 | 0.72 | IMPDH2 (0.60) | IMPDH2KDRFLT1FLT4VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |