Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 2/20 | 0.39 |
| ▸ | CTSA | P10619 | 5/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | F9 | P00740 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685104 | 0.81 | GPR3 (0.39) | KCNH2SCN10APRMT1 | |
| SCHEMBL21363208 | 0.81 | PTPN5 (0.49) | PTPN5CTSARXRARXRBRXRG | |
| SCHEMBL8125229 | 0.79 | METAP2 (0.38) | — | |
| SCHEMBL9753779 | 0.79 | RXRA (0.44) | PTPN5RXRARXRBRXRGALDH1A1 | |
| SCHEMBL2662566 | 0.77 | KDM4E (0.45) | ALDH1A1GPR139SLC6A4 | |
| SCHEMBL8640563 | 0.77 | KAT6A (0.35) | ALDH1A1SLC6A4 | |
| SCHEMBL22888490 | 0.77 | PTPN5 (0.54) | PTPN5RXRARXRBRXRGALDH1A1 | |
| SCHEMBL8143605 | 0.75 | P2RY1 (0.35) | PTPN5KDM5A | |
| SCHEMBL6299217 | 0.73 | TRPM8 (0.31) | — | |
| SCHEMBL7687621 | 0.72 | GPR3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007095383-A2 | PRODRUGS | MYRIAD GENETICS, INC. (US) | 2007-08-23 | — | — | WO | disclosed |