Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1369636 | 0.87 | RXRA (0.38) | RXRARXRBRXRGPTPN5HDAC4 | |
| SCHEMBL7179081 | 0.84 | RXRA (0.42) | RXRARXRBRXRGPTPN5HDAC4 | |
| SCHEMBL15067062 | 0.82 | LMNA (0.38) | HDAC4HDAC8KDM4EMDM4ALDH1A1 | |
| SCHEMBL6494848 | 0.81 | LMNA (0.36) | RXRARXRBRXRGPTPN5KDM4E | |
| SCHEMBL9452017 | 0.79 | CTSS (0.38) | RXRARXRBRXRGPTPN5CTSS | |
| SCHEMBL5320552 | 0.79 | PTPN5 (0.39) | RXRARXRBRXRGPTPN5ALDH1A1 | |
| SCHEMBL564584 | 0.78 | LMNA (0.34) | RXRARXRBRXRGKDM4EALDH1A1 | |
| SCHEMBL5352034 | 0.77 | RXRA (0.62) | RXRARXRBRXRGPTPN5HDAC4 | |
| SCHEMBL9599913 | 0.76 | THRB (0.36) | KDM4EALDH1A1SMN1; SMN2BRD4 | |
| SCHEMBL598181 | 0.75 | RXRA (0.66) | RXRARXRBRXRGPTPN5HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018936-A1 | PHOSPHATE ESTER FLAME RETARDANT MIXTURE AND FOAMED RESINS CONTAINING SAME | ALBRIGHT & WILSON AMERICAS INC. (US) | 1991-12-12 | — | — | WO | disclosed |