Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20362355 | 1.00 | SLC7A5 (0.50) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL13607877 | 1.00 | SLC7A5 (0.50) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL26552667 | 0.86 | HTR6 (0.44) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL22927954 | 0.86 | HTR6 (0.44) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL5329852 | 0.85 | HTR6 (0.43) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL26552691 | 0.84 | HTR6 (0.42) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL14189738 | 0.82 | HTR6 (0.41) | HTR6HDAC8KMT2AKIF11 | |
| SCHEMBL16884603 | 0.81 | HTR6 (0.42) | HTR6KDM4EMAPTKMT2A | |
| SCHEMBL15030997 | 0.81 | HTR6 (0.42) | HTR6KDM4EMAPTKMT2A | |
| SCHEMBL26008190 | 0.81 | SLC7A5 (0.47) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322859-A1 | BICYCLIC PEPTIDYL INHIBITORS | OHIO STATE INNOVATION FOUNDATION | 2023-10-12 | — | — | US | disclosed |
| US-9867845-B2 | Vectors for delivery of agents across biological membranes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-01-16 | — | — | US | disclosed |
| US-20170267689-A1 | STIMULI-SWITCHABLE MOIETIES, MONOMERS AND POLYMERS INCORPORATING STIMULI-SWITCHABLE MOIETIES, AND METHODS OF MAKING AND USING SAME | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2017-09-21 | — | — | US | disclosed |
| US-9630989-B2 | Dipeptide analogs for treating conditions associated with amyloid fibril formation | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2017-04-25 | — | — | US | disclosed |
| US-20160030590-A1 | VECTORS FOR DELIVERY OF AGENTS ACROSS BIOLOGICAL MEMBRANES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-02-04 | — | — | US | disclosed |
| US-20150322110-A1 | DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2015-11-12 | — | — | US | disclosed |
| US-9096645-B2 | Dipeptide analogs for treating conditions associated with amyloid fibril formation | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2015-08-04 | — | — | US | disclosed |
| US-20130225512-A1 | DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-08-29 | — | — | US | disclosed |
| US-20120289571-A1 | POLYMERIC CONJUGATES OF AROMATIC AMINE CONTAINING COMPOUNDS INCLUDING RELEASABLE UREA LINKER | ENZON PHARMACEUTICALS, INC. (US) | 2012-11-15 | — | — | US | disclosed |
| US-20080125452-A1 | Indolopyridines,Benzofuranopyridines and Benzothienopyridines | ALTANA PHARMA AG (DE) | 2008-05-29 | — | — | US | disclosed |
| US-20080114017-A1 | Novel Indolopyridines, Benzofuranopyridines and Benzothienopyridines | 4SC AG (DE) | 2008-05-15 | — | — | US | disclosed |
| US-20070258899-A1 | Diagnostic and therapeutic agents | KARYON-CTT LTD (FI) | 2007-11-08 | — | — | US | disclosed |
| WO-2007113385-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | KARYON-CTT LTD (FI) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114017-A1 | Novel Indolopyridines, Benzofuranopyridines and Benzothienopyridines | BAX, API5, AIFM1 | SLC7A5 4164/4885ALPI 3874/4885PKM 2198/4885 |
| US-20160030590-A1 | VECTORS FOR DELIVERY OF AGENTS ACROSS BIOLOGICAL MEMBRANES | BST2, CD2BP2, LNPEP | SLC7A5 1313/4885ALPI 3975/4885PKM 4349/4885 |
| US-20150322110-A1 | DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION | IAPP, APP, APBA1 | SLC7A5 899/4885ALPI 1362/4885PKM 3573/4885 |
| US-20170267689-A1 | STIMULI-SWITCHABLE MOIETIES, MONOMERS AND POLYMERS INCORPORATING STIMULI-SWITCHABLE MOIETIES, AND METHODS OF MAKING AND USING SAME | PASK, PAM, PTMS | SLC7A5 3582/4885ALPI 4859/4885PKM 467/4885 |
| US-20230322859-A1 | BICYCLIC PEPTIDYL INHIBITORS | NFKBIA, IKBKG, NFRKB | SLC7A5 1683/4885ALPI 4802/4885PKM 1575/4885 |
| US-20130225512-A1 | DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION | IAPP, APP, APBA1 | SLC7A5 924/4885ALPI 1601/4885PKM 3261/4885 |
| US-20120289571-A1 | POLYMERIC CONJUGATES OF AROMATIC AMINE CONTAINING COMPOUNDS INCLUDING RELEASABLE UREA LINKER | AURKA, DSTYK, TYR | SLC7A5 244/4885ALPI 1925/4885PKM 959/4885 |
| US-20080125452-A1 | Indolopyridines,Benzofuranopyridines and Benzothienopyridines | BAX, AIFM1, API5 | SLC7A5 4214/4885ALPI 3577/4885PKM 2071/4885 |
| US-20070258899-A1 | Diagnostic and therapeutic agents | YBX1, MLX, TPX2 | SLC7A5 3712/4885ALPI 533/4885PKM 3848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.