Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702096 | 0.86 | NAMPT (0.84) | NAMPTSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL3698742 | 0.79 | NAMPT (1.00) | NAMPTSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL15029231 | 0.72 | TRAP1 (0.49) | NAMPTSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL5923951 | 0.72 | TAS1R3 (0.61) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3704676 | 0.72 | NAMPT (1.00) | NAMPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL3634459 | 0.72 | RAB9A (0.67) | NAMPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL25206736 | 0.71 | NPC1 (0.58) | SMN1; SMN2NPC1RAB9AMAPTHTT | |
| SCHEMBL5319230 | 0.71 | TAS1R3 (0.52) | NAMPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL4647917 | 0.70 | NPC1 (0.77) | SMN1; SMN2NPC1RAB9AMAPTHTT | |
| Hydrochloric Acid SCHEMBL5493447 | 0.70 | SMN1; SMN2 (0.75) | NAMPTSMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848289-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | Senomyx, Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006084246-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |