Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665063 | 0.82 | RAB9A (0.43) | CA2CA1CA9RAB9ACA7 | |
| SCHEMBL30229578 | 0.81 | NOS1 (0.39) | CA2CA1CA9RAB9ASMN1; SMN2 | |
| SCHEMBL29116579 | 0.76 | CA2 (0.42) | CA2CA1CA9STSSMN1; SMN2 | |
| SCHEMBL8732546 | 0.76 | CCR5 (0.45) | SRCSKP2CYP19A1ALOX5CCR5 | |
| SCHEMBL9499381 | 0.74 | MEN1 (0.34) | CA2CA1CA9STSSMN1; SMN2 | |
| SCHEMBL21550397 | 0.73 | TAAR1 (0.40) | CA2CA1CA9RAB9ACA7 | |
| SCHEMBL6586893 | 0.72 | ALDH1A1 (0.48) | CA2CA1CA9RAB9ACA7 | |
| SCHEMBL21550420 | 0.72 | PTGES2 (0.40) | CA2CA1CA9SMN1; SMN2CA7 | |
| SCHEMBL2932203 | 0.72 | RAB9A (0.53) | CA2CA1CA9RAB9ASMN1; SMN2 | |
| SCHEMBL6491477 | 0.71 | CA2 (0.45) | CA2CA1CA9STSSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106554-A2 | TREATMENT AND PREVENTION OF VASCULAR HYPERPLASIA USING POLYAMINE AND POLYAMINE ANALOG COMPOUNDS | PROGEN PHARMACEUTICALS, INC. (US) | 2007-09-20 | — | — | WO | disclosed |