Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 8/20 | 0.40 |
| ▸ | CA1 | P00915 | 7/20 | 0.40 |
| ▸ | CA7 | P43166 | 7/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 5/20 | 0.32 |
| ▸ | CA6 | P23280 | 4/20 | 0.32 |
| ▸ | CA9 | Q16790 | 4/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321971 | 0.82 | CA2 (0.44) | RAB9ACA2CA1CA7CA13 | |
| SCHEMBL2932203 | 0.77 | RAB9A (0.53) | RAB9ACA2CA1CA7CA13 | |
| SCHEMBL30229578 | 0.76 | NOS1 (0.39) | RAB9ACA2CA1CA7CA13 | |
| SCHEMBL6586893 | 0.74 | ALDH1A1 (0.48) | RAB9ACA2CA1CA7CA13 | |
| SCHEMBL28166915 | 0.73 | PGK1 (0.46) | SLC11A2PGK1PGK2 | |
| SCHEMBL29106965 | 0.73 | CA2 (0.35) | CA2CA1CA7CA13CA12 | |
| SCHEMBL2933802 | 0.72 | RAB9A (0.47) | RAB9ACA2CA1CA7CA13 | |
| SCHEMBL21550397 | 0.72 | TAAR1 (0.40) | RAB9ACA2CA1CA7CA13 | |
| SCHEMBL21550420 | 0.71 | PTGES2 (0.40) | CA2CA1CA7CA13CA12 | |
| SCHEMBL20000078 | 0.69 | ALDH1A1 (0.34) | CA2CA1CA7CA13CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453787-A1 | CYCLOALKYL SUBSTITUTED POLYAMINES FOR CANCER THERAPY AND METHODS OF SYNTHESIS THEREFOR | SLIL Biomedical Corporation (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050072-A1 | CYCLOALKYL SUBSTITUTED POLYAMINES FOR CANCER THERAPY AND METHODS OF SYNTHESIS THEREFOR | SLIL BIOMEDICAL CORPORATION (US) | 2003-06-19 | — | — | WO | disclosed |