Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368779 | 0.86 | TDP1 (0.46) | CYP3A4CYP2D6CYP2C19TACR1MEN1 | |
| SCHEMBL5321171 | 0.85 | HTT (0.44) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5321030 | 0.85 | LMNA (0.46) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12861282 | 0.82 | OPRM1 (0.49) | MEN1KMT2AOPRM1OPRL1ALDH1A1 | |
| SCHEMBL5323549 | 0.81 | GAA (0.43) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15590888 | 0.71 | L3MBTL1 (0.49) | MEN1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL16788643 | 0.71 | L3MBTL1 (0.49) | MEN1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL5320282 | 0.71 | MEN1 (0.48) | CYP1A2CYP2C9NPSR1TACR1MEN1 | |
| SCHEMBL13452589 | 0.71 | ADRA2B (0.50) | NPSR1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL14017766 | 0.71 | ADRA2B (0.50) | NPSR1MEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007095756-A1 | NOVEL CENTRAL-NERVOUS SYSTEM ACTING COMPOUNDS AND METHODS FOR THE TREATMENT OF CNS DISORDERS | CLERA INC. (CA) | 2007-08-30 | — | — | WO | disclosed |