SCHEMBL5323626

SCHEMBL5323626

CC(C)C[C@H](C(=O)N1CCNC[C@]1(C)c1ccc(Cl)s1)[C@H](O)C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5316333 0.82 ADAM17 (0.38)
SCHEMBL5316256 0.81 NPC1 (0.32)
SCHEMBL5318276 0.81 NPC1 (0.32)
SCHEMBL5320170 0.80 MC4R (0.34)
SCHEMBL5317625 0.79 MMP1 (0.34)
SCHEMBL5395845 0.79 MMP1 (0.35)
SCHEMBL5324832 0.78 HPGD (0.34)
SCHEMBL5318581 0.78 SLC6A2 (0.31) HCAR2
SCHEMBL5324960 0.78 SLC6A2 (0.31) HCAR2
SCHEMBL5322497 0.78 SLC6A2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1771421-A1 N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF Applied Research Systems ARS Holding N.V. (AN) 2007-04-11 EP disclosed
WO-2006010751-A1 N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 2006-02-02 WO disclosed