Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5395845 | 0.97 | MMP1 (0.35) | MMP1MMP2POLBPKMMMP9 | |
| SCHEMBL5322497 | 0.90 | SLC6A2 (0.36) | POLBHSD17B10ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL5318347 | 0.90 | ALDH1A1 (0.35) | OPRM1OPRD1ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL5324832 | 0.87 | HPGD (0.34) | MMP1MMP2MMP8ALDH1A1KMT2A | |
| SCHEMBL5316662 | 0.87 | MTNR1B (0.37) | MC4ROPRM1SLC6A2SLC6A4 | |
| SCHEMBL5319325 | 0.84 | CCR1 (0.34) | MMP1MMP2MMP3MMP8 | |
| SCHEMBL5464768 | 0.83 | SCN7A (0.33) | MAPK1SMN1; SMN2 | |
| SCHEMBL5319634 | 0.83 | MMP2 (0.43) | MMP1MMP2MMP9MMP3MMP8 | |
| SCHEMBL5316333 | 0.82 | ADAM17 (0.38) | ALDH1A1CYP2D6MAPK1SLC6A2SLC6A4 | |
| SCHEMBL5419543 | 0.82 | ALDH1A1 (0.35) | PKMALDH1A1L3MBTL1SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010751-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-02-02 | — | — | WO | disclosed |