Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.34 |
| ▸ | CHRNG | P07510 | 3/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | CHRND | Q07001 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319409 | 0.91 | MMP2 (0.41) | ADAM17SLC6A4SLC6A2SLC6A3CHRNA1 | |
| SCHEMBL5318347 | 0.88 | ALDH1A1 (0.35) | SLC6A4SLC6A2SLC6A3KDM4EALDH1A1 | |
| SCHEMBL5368861 | 0.84 | CETP (0.31) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5320170 | 0.83 | MC4R (0.34) | — | |
| SCHEMBL5317625 | 0.82 | MMP1 (0.34) | SLC6A4SLC6A2SLC6A3MAPK1ALDH1A1 | |
| SCHEMBL5419543 | 0.82 | ALDH1A1 (0.35) | SLC6A4SLC6A3KDM4EALDH1A1TP53 | |
| SCHEMBL5323626 | 0.82 | HCAR3 (0.30) | — | |
| SCHEMBL5324832 | 0.82 | HPGD (0.34) | ALDH1A1CTSKCCR1 | |
| SCHEMBL5384481 | 0.81 | TAS1R3 (0.34) | SLC6A4SLC6A2 | |
| SCHEMBL5372203 | 0.81 | GPR183 (0.35) | KDM4EALDH1A1HTR2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010751-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-02-02 | — | — | WO | disclosed |