Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316256 | 1.00 | NPC1 (0.32) | NPC1THRBHPGDRAB9AL3MBTL1 | |
| SCHEMBL5320650 | 0.91 | MMP2 (0.41) | NPC1THRBHPGDRAB9AL3MBTL1 | |
| SCHEMBL5319597 | 0.91 | MMP2 (0.41) | NPC1THRBHPGDRAB9AL3MBTL1 | |
| SCHEMBL5323626 | 0.81 | HCAR3 (0.30) | — | |
| SCHEMBL5320170 | 0.80 | MC4R (0.34) | NPC1 | |
| SCHEMBL5316333 | 0.80 | ADAM17 (0.38) | THRB | |
| SCHEMBL5341256 | 0.80 | MMP2 (0.39) | — | |
| SCHEMBL5322497 | 0.78 | SLC6A2 (0.36) | HPGDL3MBTL1 | |
| SCHEMBL5334753 | 0.78 | MMP2 (0.41) | L3MBTL1 | |
| SCHEMBL5317625 | 0.78 | MMP1 (0.34) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010751-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-02-02 | — | — | WO | disclosed |