Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317625 | 0.87 | MMP1 (0.34) | ALDH1A1KMT2AMMP1MMP2MMP8 | |
| SCHEMBL5322497 | 0.85 | SLC6A2 (0.36) | HPGDALDH1A1KMT2A | |
| SCHEMBL5395845 | 0.85 | MMP1 (0.35) | HPGDMEN1ALDH1A1KMT2ACTSK | |
| SCHEMBL5464768 | 0.84 | SCN7A (0.33) | — | |
| SCHEMBL5319325 | 0.83 | CCR1 (0.34) | MCL1MMP1MMP2MMP8CCR1 | |
| SCHEMBL5316333 | 0.82 | ADAM17 (0.38) | ALDH1A1CTSKCCR1 | |
| SCHEMBL5368861 | 0.81 | CETP (0.31) | — | |
| SCHEMBL5345342 | 0.81 | MMP2 (0.44) | MMP1MMP2MMP8 | |
| SCHEMBL5419543 | 0.81 | ALDH1A1 (0.35) | ALDH1A1MCL1 | |
| SCHEMBL5384481 | 0.80 | TAS1R3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010751-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-02-02 | — | — | WO | disclosed |