SCHEMBL5323645

SCHEMBL5323645

COc1cccc(C=CC(C)=O)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.68
FOS P01100 1/20 0.68
JUN P05412 1/20 0.68
BCHE P06276 1/20 0.68
CYP1A2 P05177 4/20 0.62
CYP2D6 P10635 4/20 0.62
CYP1A1 P04798 3/20 0.62
CYP1B1 Q16678 3/20 0.62
ABCG2 Q9UNQ0 3/20 0.62
MAOA P21397 2/20 0.62
NR1H4 Q96RI1 3/20 0.61
RELA Q04206 2/20 0.61
NPC1 O15118 1/20 0.61
LMNA P02545 1/20 0.61
MAPT P10636 1/20 0.61
HPGD P15428 1/20 0.61
NFKB1 P19838 1/20 0.61
RAB9A P51151 1/20 0.61
NFKB2 Q00653 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2632249 1.00 MAOB (0.68) MAOBFOSJUNBCHECYP1A2
SCHEMBL29374516 1.00 MAOB (0.68) MAOBFOSJUNBCHECYP1A2
SCHEMBL23273962 0.89 MAOB (0.63) MAOBFOSJUNBCHECYP1A2
SCHEMBL23273963 0.89 MAOB (0.63) MAOBFOSJUNBCHECYP1A2
SCHEMBL15932965 0.89 MAOB (0.58) MAOBFOSJUNBCHECYP1A2
SCHEMBL3580362 0.88 FOS (0.79) MAOBFOSJUNBCHECYP1A2
SCHEMBL3580365 0.88 FOS (0.79) MAOBFOSJUNBCHECYP1A2
SCHEMBL29822711 0.88 FOS (0.79) MAOBFOSJUNBCHECYP1A2
SCHEMBL80787 0.86 FOS (0.72) MAOBFOSJUNBCHECYP1A2
SCHEMBL30584119 0.86 FOS (0.72) MAOBFOSJUNBCHECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118255708-A Polysubstituted carbazole derivative and synthesis method thereof 重庆理工大学 2024-06-28 CN claimed
CN-1882602-A Modulation and degradation of hyaluronan synthesis in the treatment of disease MEDITECH RES LTD (AU) 2006-12-20 CN claimed
CN-1681470-A Agent for dyeing keratinous fibres HENKEL KGAA (DE) 2005-10-12 CN claimed
EP-4727923-A1 TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA University of Georgia Research Foundation, Inc. (US) 2026-04-22 EP disclosed
US-20260098012-A1 TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA UNIV GEORGIA (US) 2026-04-09 US disclosed
EP-3930849-B1 THIAZOLE DERIVATIVES AS PROTEIN SECRETION INHIBITORS KEZAR LIFE SCIENCES (US) 2025-02-19 EP disclosed
WO-2024258904-A1 TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2024-12-19 WO disclosed
CN-118255708-A Polysubstituted carbazole derivative and synthesis method thereof 重庆理工大学 2024-06-28 CN disclosed
CN-113304129-B Application of mono-ketene monocarbonyl curcumin analogue in preparing antioxidant drugs 温州医科大学附属第二医院(温州医科大学附属育英儿童医院) 2022-11-08 CN disclosed
US-20220289657-A1 COMPOSITION FOR PREVENTING OR TREATING BACTERIAL INFECTIOUS DISEASE COMPRISING 4-GINGEROL DERIVATIVE COMPOUND AS ACTIVE INGREDIENT KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS (KR) 2022-09-15 US disclosed
US-20220153732-A1 PROTEIN SECRETION INHIBITORS ENODIA THERAPEUTICS SAS (FR) 2022-05-19 US disclosed
EP-0146271-A2 Aralykyl (arylethynyl) aralkyl amines for use as vasodilators and antihypertensives McNeilab, Inc. (US) 1985-06-26 EP disclosed
EP-0145361-A2 Acetylene derivatives for the treatment of hypertension and angina McNeilab, Inc. (US) 1985-06-19 EP disclosed
US-4293391-A Cadmium plating baths and methods for electrodepositing bright cadmium deposits ROHCO, INC. (US) 1981-10-06 US disclosed
US-4270989-A AN AQUEOUS SOLUTION OF A IONIZABLE CADMIUM COMPOUND, A FREE ACID, AND AN ALKYLENE OXIDE ADDUCT OR A POLYOXYALKYLENE GLYCOL HAVING A PHOSPHATE, CARBOXYLATE, OR ARYL SULFATE GROUP ROHCO, INC. (US) 1981-06-02 US disclosed
US-4229268-A SULFUR-CONTAINING POLYOXYALKYLENE GLYCOL IN BATHS ROHCO, INC. (US) 1980-10-21 US disclosed
US-4162947-A AROMATIC SULFONIC ACID OR SALT, ZINC AND AMMONIUM COMPOUNDS R. O. HULL & COMPANY, INC. (US) 1979-07-31 US disclosed
US-4146441-A Additive compositions, baths, and methods for electrodepositing bright zinc deposits R. O. HULL & COMPANY, INC. (US) 1979-03-27 US disclosed
US-4146442-A Zinc electroplating baths and process R. O. HULL & COMPANY, INC. (US) 1979-03-27 US disclosed
US-4075066-A Electroplating zinc, ammonia-free acid zinc plating bath therefor and additive composition therefor R. O. HULL & COMPANY, INC. (US) 1978-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098012-A1 TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA CD47, SLC11A2, G6PD MAOB 4337/4885FOS 4508/4885JUN 4850/4885
US-20220289657-A1 COMPOSITION FOR PREVENTING OR TREATING BACTERIAL INFECTIOUS DISEASE COMPRISING 4-GINGEROL DERIVATIVE COMPOUND AS ACTIVE INGREDIENT HSD11B1, GRHPR, TIPRL MAOB 4774/4885FOS 2502/4885JUN 2500/4885
US-20220153732-A1 PROTEIN SECRETION INHIBITORS SEC61B, SEC61A1, SEC61G MAOB 3887/4885FOS 3374/4885JUN 2627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.