SCHEMBL5323946

SCHEMBL5323946

NC(Cc1ccnnc1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 1.00
SLC7A5 Q01650 4/20 0.56
PTGS1 P23219 3/20 0.56
PKM P14618 2/20 0.56
ALPI P09923 1/20 0.56
XIAP P98170 1/20 0.56
LOXL2 Q9Y4K0 1/20 0.52
CYP1A2 P05177 2/20 0.50
HIF1A Q16665 3/20 0.49
ALOX15 P16050 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
KDM4E B2RXH2 1/20 0.49
USP2 O75604 1/20 0.49
EGFR P00533 1/20 0.49
LCK P06239 1/20 0.49
FYN P06241 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
HTR2A P28223 1/20 0.49
PTGS2 P35354 1/20 0.49
RECQL P46063 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31000639 1.00 HSD17B10 (1.00) HSD17B10SLC7A5PTGS1PKMALPI
SCHEMBL5322269 0.83 HSD17B10 (0.71) HSD17B10SLC7A5PTGS1PKMALPI
SCHEMBL288024 0.79 SLC7A5 (0.68) HSD17B10SLC7A5PTGS1PKMALPI
SCHEMBL122533 0.79 SLC7A5 (0.68) HSD17B10SLC7A5PTGS1PKMALPI
SCHEMBL122532 0.79 SLC7A5 (0.68) HSD17B10SLC7A5PTGS1PKMALPI
SCHEMBL21947598 0.79 HSD17B10 (0.65) HSD17B10SLC7A5PTGS1PKMALPI
Hydrochloric Acid SCHEMBL7327198 0.78 SLC7A5 (0.66) HSD17B10SLC7A5PTGS1PKMALPI
Hydrochloric Acid SCHEMBL5966996 0.78 SLC7A5 (0.66) HSD17B10SLC7A5PTGS1PKMALPI
Hydrochloric Acid SCHEMBL29401033 0.78 SLC7A5 (0.66) HSD17B10SLC7A5PTGS1PKMALPI
Hydrochloric Acid SCHEMBL7327202 0.78 SLC7A5 (0.66) HSD17B10SLC7A5PTGS1PKMALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220232831-A1 NOVEL NON-CODING HETEROCYCLIC AMINO ACIDS (NCHAA) AND THEIR USE AS HERBICIDES FORTEPHEST LTD. (IL) 2022-07-28 US claimed
EP-3983382-A1 NOVEL NON-CODING HETEROCYCLIC AMINO ACIDS (NCHAA) AND THEIR USE AS HERBICIDES Fortephest Ltd. (IL) 2022-04-20 EP claimed
WO-2020250223-A1 NOVEL NON-CODING HETEROCYCLIC AMINO ACIDS (NCHAA) AND THEIR USE AS HERBICIDES FORTEPHEST LTD. (IL) 2020-12-17 WO claimed
US-20220232831-A1 NOVEL NON-CODING HETEROCYCLIC AMINO ACIDS (NCHAA) AND THEIR USE AS HERBICIDES FORTEPHEST LTD. (IL) 2022-07-28 US disclosed
EP-3983382-A1 NOVEL NON-CODING HETEROCYCLIC AMINO ACIDS (NCHAA) AND THEIR USE AS HERBICIDES Fortephest Ltd. (IL) 2022-04-20 EP disclosed
CN-113939499-A Novel non-coding heterocyclic amino acids (NCHAA) and their use as herbicides 福提费斯特有限公司 2022-01-14 CN disclosed
WO-2020250223-A1 NOVEL NON-CODING HETEROCYCLIC AMINO ACIDS (NCHAA) AND THEIR USE AS HERBICIDES FORTEPHEST LTD. (IL) 2020-12-17 WO disclosed
US-20070258899-A1 Diagnostic and therapeutic agents KARYON-CTT LTD (FI) 2007-11-08 US disclosed
WO-2007113385-A1 DIAGNOSTIC AND THERAPEUTIC AGENTS KARYON-CTT LTD (FI) 2007-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220232831-A1 NOVEL NON-CODING HETEROCYCLIC AMINO ACIDS (NCHAA) AND THEIR USE AS HERBICIDES SLC43A1, NPPA, NAAA HSD17B10 2268/4885SLC7A5 61/4885PTGS1 4007/4885
US-20070258899-A1 Diagnostic and therapeutic agents YBX1, MLX, TPX2 HSD17B10 4778/4885SLC7A5 3712/4885PTGS1 1844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.