Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867873 | 0.85 | DPP4 (0.42) | SIGMAR1HTR2CHTR2B | |
| SCHEMBL11835662 | 0.84 | ADRB2 (0.35) | HSD17B10SIGMAR1HTR2CHTR2B | |
| SCHEMBL10409487 | 0.83 | SIGMAR1 (0.39) | SIGMAR1 | |
| SCHEMBL14785647 | 0.81 | MAOA (0.41) | HSD17B10MAOAHTR3EHTR3BADRB1 | |
| SCHEMBL659344 | 0.79 | MAOA (0.49) | MAOAHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL14833501 | 0.77 | MAOA (0.43) | MAOAHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL7584165 | 0.77 | CALM1 (0.42) | MAOASIGMAR1DRD2KCNH2REN | |
| SCHEMBL11712199 | 0.77 | HRH3 (0.49) | SIGMAR1KCNH2 | |
| SCHEMBL9527372 | 0.75 | HTR2C (0.46) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL10409483 | 0.75 | SLC6A2 (0.40) | HTR2CCHRNA7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007000771-A2 | FUSED QUINAZOLINONE DERIVATIVES AND USES THEREOF | RIMONYX PHARMACEUTICALS LTD. (IL) | 2007-01-04 | — | — | WO | disclosed |