Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323684 | 0.90 | TSHR (0.40) | TSHRKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL5328330 | 0.88 | THRB (0.43) | TSHRKMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL5331463 | 0.84 | TSHR (0.38) | TSHRKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL5326299 | 0.84 | L3MBTL1 (0.49) | KDM4EALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL5328482 | 0.83 | ALDH1A1 (0.52) | TSHRKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL5324510 | 0.82 | THRB (0.38) | ALDH1A1MAPTSMN1; SMN2LMNARAB9A | |
| SCHEMBL5329550 | 0.80 | THRB (0.39) | KDM4EALDH1A1MAPTKMT2APOLB | |
| SCHEMBL5326354 | 0.79 | THRB (0.51) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPK1 | |
| SCHEMBL5326859 | 0.78 | THRB (0.46) | — | |
| SCHEMBL5323874 | 0.77 | RORC (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | claimed |