Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327964 | 0.88 | THRB (0.47) | THRBTHRA | |
| SCHEMBL5323684 | 0.86 | TSHR (0.40) | TSHRTHRBKMT2ALMNAMAPK1 | |
| SCHEMBL5326354 | 0.84 | THRB (0.51) | MCOLN3THRBKMT2ANPC1MEN1 | |
| SCHEMBL5327154 | 0.84 | TSHR (0.43) | TSHRKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL5328482 | 0.84 | ALDH1A1 (0.52) | TSHRTHRBKMT2ALMNAALDH1A1 | |
| SCHEMBL5326299 | 0.81 | L3MBTL1 (0.49) | THRBKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL5329550 | 0.77 | THRB (0.39) | THRBKMT2ANPC1MEN1LMNA | |
| SCHEMBL5328999 | 0.76 | THRB (0.52) | THRBKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL5324510 | 0.76 | THRB (0.38) | THRBLMNAALDH1A1RAB9ATDP1 | |
| SCHEMBL5323874 | 0.75 | RORC (0.55) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | claimed |
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | disclosed |