Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323252 | 0.90 | PTGS2 (0.35) | MAPTSMN1; SMN2PTGS2HTTLMNA | |
| SCHEMBL5321578 | 0.89 | PTGS2 (0.37) | MAPTSMN1; SMN2PTGS2HTTLMNA | |
| SCHEMBL14622407 | 0.83 | PTGS2 (0.38) | MAPTSMN1; SMN2PTGS2HTTLMNA | |
| SCHEMBL5325599 | 0.83 | KDM4E (0.38) | MAPTSMN1; SMN2PTGS2HTTLMNA | |
| SCHEMBL5321659 | 0.82 | ALOX15 (0.43) | MAPTSMN1; SMN2HTTLMNAGAA | |
| SCHEMBL5331474 | 0.82 | PTGS2 (0.38) | MAPTSMN1; SMN2PTGS2HTTLMNA | |
| SCHEMBL5285665 | 0.81 | HSD17B10 (0.35) | MAPTSMN1; SMN2PTGS2HTTLMNA | |
| SCHEMBL5329856 | 0.81 | DNM1 (0.45) | DNM1SMN1; SMN2LMNAGAATHRB | |
| SCHEMBL5325697 | 0.81 | RAD51 (0.40) | SMN1; SMN2PTGS2HTTLMNATHRB | |
| SCHEMBL5324453 | 0.81 | CSF1R (0.40) | MAPTPTGS2HTTLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |