Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325599 | 0.91 | KDM4E (0.38) | HSD17B10ALDH1A1PRMT5WDR77POLB | |
| SCHEMBL14622410 | 0.89 | MAPT (0.43) | ALDH1A1PRMT5WDR77POLBKDM4E | |
| SCHEMBL5321659 | 0.88 | ALOX15 (0.43) | HSD17B10ALDH1A1POLBKDM4EMAPT | |
| SCHEMBL5322150 | 0.85 | KDM4E (0.38) | HSD17B10ALDH1A1POLBKDM4EMAPT | |
| SCHEMBL5325651 | 0.85 | LMNA (0.47) | HSD17B10ALDH1A1POLBKDM4EMAPT | |
| SCHEMBL5323186 | 0.84 | MAPT (0.51) | ALDH1A1POLBKDM4EMAPTMAPK1 | |
| SCHEMBL5321578 | 0.84 | PTGS2 (0.37) | MAPTSMN1; SMN2HTTLMNAPTGS2 | |
| SCHEMBL5323252 | 0.83 | PTGS2 (0.35) | MAPTMAPK1SMN1; SMN2HTTLMNA | |
| SCHEMBL14622908 | 0.82 | DRD2 (0.38) | — | |
| SCHEMBL5285676 | 0.82 | HSD17B10 (0.36) | HSD17B10ALDH1A1PRMT5WDR77POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |