Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 13/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14622465 | 0.90 | DNM1 (0.44) | DNM1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5328787 | 0.89 | DNM1 (0.44) | DNM1KDM4EALDH1A1MEN1LMNA | |
| SCHEMBL5329851 | 0.88 | KDM4E (0.43) | DNM1KDM4EALDH1A1MEN1LMNA | |
| SCHEMBL5321578 | 0.83 | PTGS2 (0.37) | LMNASMN1; SMN2THRB | |
| SCHEMBL14622410 | 0.83 | MAPT (0.43) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL5323252 | 0.82 | PTGS2 (0.35) | LMNASMN1; SMN2RAB9ATHRB | |
| SCHEMBL5322868 | 0.82 | ALDH1A1 (0.39) | DNM1KDM4EALDH1A1MEN1LMNA | |
| SCHEMBL5327487 | 0.81 | DNM1 (0.34) | DNM1LMNASMN1; SMN2GAATHRB | |
| SCHEMBL14622407 | 0.78 | PTGS2 (0.38) | ALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL5325599 | 0.78 | KDM4E (0.38) | KDM4EALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |