Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | BRD1 | O95696 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.41 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533055 | 0.88 | ALDH1A1 (0.45) | MAPTALDH1A1RECQLFFAR4KDM4E | |
| SCHEMBL532880 | 0.88 | FFAR4 (0.56) | MAPTALDH1A1RECQLFFAR4MCOLN2 | |
| SCHEMBL533017 | 0.87 | FFAR4 (0.55) | MAPTALDH1A1RECQLFFAR4KDM4E | |
| SCHEMBL533437 | 0.85 | CYTH2 (0.49) | MAPTALDH1A1RECQLFFAR4KDM4E | |
| SCHEMBL533666 | 0.85 | FFAR4 (0.56) | MAPTALDH1A1RECQLFFAR4POLB | |
| SCHEMBL532776 | 0.85 | FFAR4 (0.54) | MAPTALDH1A1RECQLFFAR4POLB | |
| SCHEMBL533091 | 0.83 | BRPF1 (0.52) | MAPTALDH1A1RECQLBRPF1KDM4E | |
| SCHEMBL532953 | 0.83 | FFAR4 (0.59) | MAPTALDH1A1FFAR4SMN1; SMN2KMT2A | |
| SCHEMBL534077 | 0.83 | TSHR (0.47) | MAPTALDH1A1RECQLFFAR4POLB | |
| SCHEMBL533020 | 0.83 | KMT2A (0.51) | MAPTALDH1A1RECQLBRPF1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415760-A2 | CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2012-02-08 | — | — | EP | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |