Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 6/20 | 0.38 |
| ▸ | PAM | P19021 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324746 | 0.89 | FAAH (0.40) | CASP1FAAH | |
| SCHEMBL5331537 | 0.84 | TSHR (0.46) | TSHRKLK7CASP1FAAHALDH1A1 | |
| SCHEMBL5331113 | 0.82 | TSHR (0.43) | TSHRKLK7FAAH | |
| SCHEMBL5324608 | 0.80 | ADRB2 (0.42) | TSHRPAMCASP1MAOBALDH1A1 | |
| SCHEMBL5324557 | 0.76 | TSHR (0.46) | TSHRKLK7ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL25297801 | 0.75 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1 | |
| SCHEMBL25298888 | 0.74 | NPC1 (0.46) | ALDH1A1 | |
| SCHEMBL5324750 | 0.72 | TDP1 (0.43) | CASP1 | |
| SCHEMBL5331057 | 0.72 | FAAH (0.38) | CASP1FAAHL3MBTL1 | |
| SCHEMBL5331609 | 0.68 | TSHR (0.43) | TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146086-A1 | CREATINE PRODRUGS, COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2007-12-21 | — | — | WO | disclosed |