Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331343 | 1.00 | PLG (0.37) | PLGPLATLMNATHRATHRB | |
| SCHEMBL2533711 | 0.94 | PLG (0.33) | PLGPLATLMNATHRATHRB | |
| SCHEMBL10826339 | 0.94 | PLG (0.33) | PLGPLATLMNATHRATHRB | |
| SCHEMBL10926810 | 0.94 | PLG (0.33) | PLGPLATLMNATHRATHRB | |
| SCHEMBL16203169 | 0.84 | CYP19A1 (0.41) | CYP19A1POLBMAPTTDP1MEN1 | |
| SCHEMBL4482942 | 0.82 | CYP2C9 (0.41) | PLGPLATLMNATHRATHRB | |
| SCHEMBL7522154 | 0.82 | CYP2C9 (0.41) | PLGPLATLMNATHRATHRB | |
| Methylene Chloride SCHEMBL28166563 | 0.82 | — | — | |
| SCHEMBL11758964 | 0.80 | LMNA (0.39) | PLGPLATLMNATHRATHRB | |
| SCHEMBL8774202 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240391870-A1 | IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY | ARCTURUS THERAPEUTICS, INC. | 2024-11-28 | — | — | US | disclosed |
| EP-4430026-A1 | IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY | Arcturus Therapeutics, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| CN-118451059-A | Ionizable cationic lipids for RNA delivery | 阿克丘勒斯治疗公司 | 2024-08-06 | — | — | CN | disclosed |
| US-20230295081-A1 | IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY | ARCTURUS THERAPEUTICS, INC. | 2023-09-21 | — | — | US | disclosed |
| US-20230295081-A1 | IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY | ARCTURUS THERAPEUTICS, INC. | 2023-09-21 | — | — | US | disclosed |
| US-20230295081-A1 | IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY | ARCTURUS THERAPEUTICS, INC. | 2023-09-21 | — | — | US | disclosed |
| US-11752128-B2 | Benzimidazoles and indoles as taro inhibitors | MERCK SHARP & DOHME CORPORATION (US) | 2023-09-12 | — | — | US | disclosed |
| EP-3389785-B1 | BENZIMIDAZOLES AND INDOLES AS TARO INHIBITORS | MERCK SHARP & DOHME (US) | 2023-08-16 | — | — | EP | disclosed |
| WO-2023086514-A1 | IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY | ARCTURUS THERAPEUTICS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| WO-2023086514-A1 | IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY | ARCTURUS THERAPEUTICS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| US-10597378-B2 | Tetrahydroisoquinolines for use as MOR/NOP dual agonists | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2020-03-24 | — | — | US | disclosed |
| US-20190077786-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2019-03-14 | — | — | US | disclosed |
| EP-3389785-A1 | BENZIMIDAZOLES AND INDOLES AS TARO INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2018-10-24 | — | — | EP | disclosed |
| WO-2017106134-A1 | BENZIMIDAZOLES AND INDOLES AS TARO INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-06-22 | — | — | WO | disclosed |
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | disclosed |
| EP-0820976-B1 | FLUORINE-SUBSTITUTED LIQUID-CRYSTAL COMPOUND, LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY DEVICE | CHISSO CORP (JP) | 2001-02-21 | — | — | EP | disclosed |
| US-6051288-A | LARGE DIELECTRIC ANISOTROPY, SMALL CHANGE IN THRESHOLD VOLTAGE DEPENDING ON TEMPERATURE, AND AN IMPROVED SOLUBILITY TO OTHER LIQUID CRYSTAL MATERIALS AT LOW TEMPERATURES | CHISSO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |
| EP-0820976-A1 | FLUORINE-SUBSTITUTED LIQUID-CRYSTAL COMPOUND, LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-4480117-A | 1-(ALKYLCYCLOHEXYL-), 2-(ALKYLCYCLOHEXANECARBONYLOXYPHENYL-)ETHANE | DAINIPPIN INK AND CHEMICALS, INC. (JP) | 1984-10-30 | — | — | US | disclosed |
| US-4293434-A | CONTAINING DYES AND AN AROMATIC ESTER COMPOUND HAVING A CYCLOHEXANE RING | VEB Werk fur Fernsehelektronik Berlin im VEB Kombinat Mikroelektronik (DD) | 1981-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10597378-B2 | Tetrahydroisoquinolines for use as MOR/NOP dual agonists | OPRL1, OPRM1, OPRK1 | PLG 4707/4885PLAT 4787/4885LMNA 3735/4885 |
| US-20240391870-A1 | IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY | NSUN3, POLRMT, NPC1L1 | PLG 2316/4885PLAT 3888/4885LMNA 1041/4885 |
| US-20230295081-A1 | IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY | NSUN3, POLRMT, NPC1L1 | PLG 2316/4885PLAT 3888/4885LMNA 1041/4885 |
| US-20190077786-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | OPRM1, OPRL1, OPRK1 | PLG 2939/4885PLAT 3460/4885LMNA 2323/4885 |
| US-11752128-B2 | Benzimidazoles and indoles as taro inhibitors | CSDE1, IDO1, TMBIM6 | PLG 4463/4885PLAT 4491/4885LMNA 3427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.