Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327792 | 0.92 | HTR6 (0.52) | HTR6DRD2DRD4DRD3HSD17B10 | |
| SCHEMBL5333018 | 0.88 | DDR1 (0.43) | HTR6HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL5332522 | 0.86 | HSD17B10 (0.42) | HTR6HSD17B10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5331983 | 0.86 | HTR6 (0.52) | HTR6HSD17B10KDM4EALDH1A1KMT2A | |
| SCHEMBL5334580 | 0.86 | ALDH1A1 (0.44) | HTR6DRD2DRD4DRD3HSD17B10 | |
| SCHEMBL5337329 | 0.86 | DRD2 (0.44) | HTR6DRD2DRD4DRD3HSD17B10 | |
| SCHEMBL5335593 | 0.83 | MPO (0.46) | HTR6DRD2DRD4DRD3KDM4E | |
| SCHEMBL5333028 | 0.82 | MPO (0.47) | HTR6DRD2DRD4DRD3MPO | |
| SCHEMBL5331060 | 0.82 | ALDH1A1 (0.46) | HTR6HSD17B10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5332975 | 0.80 | HTR6 (0.50) | HTR6ALDH1A1KMT2ADDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |