Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333246 | 0.92 | POLB (0.45) | ALDH1A1MAPTHSD17B10KMT2AKDM4E | |
| SCHEMBL5332522 | 0.90 | HSD17B10 (0.42) | ALDH1A1MAPTHSD17B10KMT2AKDM4E | |
| SCHEMBL5335240 | 0.88 | ALDH1A1 (0.44) | ALDH1A1MAPTHSD17B10KMT2AKDM4E | |
| SCHEMBL5337329 | 0.88 | DRD2 (0.44) | ALDH1A1MAPTHSD17B10KMT2AKDM4E | |
| SCHEMBL5333018 | 0.86 | DDR1 (0.43) | ALDH1A1HSD17B10KMT2AKDM4EPOLB | |
| SCHEMBL5330544 | 0.86 | HTR6 (0.43) | ALDH1A1HSD17B10KMT2AKDM4EALOX15 | |
| SCHEMBL5336272 | 0.83 | HSD17B10 (0.45) | ALDH1A1MAPTHSD17B10KMT2AKDM4E | |
| SCHEMBL5331983 | 0.82 | HTR6 (0.52) | ALDH1A1MAPTHSD17B10KMT2AKDM4E | |
| SCHEMBL5335199 | 0.82 | HTR6 (0.46) | ALDH1A1MAPTHSD17B10KMT2AKDM4E | |
| SCHEMBL5331060 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPTHSD17B10KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |