Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988719 | 1.00 | ACACB (0.37) | ACACBMAPTGPBAR1CYSLTR1MTNR1A | |
| SCHEMBL2088447 | 0.92 | ACACB (0.37) | ACACBMAPTGPBAR1CYSLTR1MTNR1A | |
| SCHEMBL122883 | 0.84 | ACACB (0.45) | ACACBMAPTGPBAR1CYSLTR1MTNR1A | |
| SCHEMBL1004145 | 0.83 | MCHR1 (0.36) | MTNR1AMTNR1BMCHR1 | |
| SCHEMBL386596 | 0.80 | ACACB (0.35) | ACACBMCHR1 | |
| SCHEMBL28887160 | 0.79 | — | — | |
| SCHEMBL2094760 | 0.79 | MCHR1 (0.39) | MAPTGPBAR1CYSLTR1MTNR1AMTNR1B | |
| SCHEMBL9442681 | 0.78 | MTNR1A (0.31) | MTNR1AMTNR1B | |
| SCHEMBL2502270 | 0.78 | MCHR1 (0.39) | MTNR1AMTNR1BMCHR1HSD17B10 | |
| SCHEMBL28897940 | 0.77 | ALDH1A1 (0.42) | MAPTSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232120-B | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2- (1H) -ones | 爱尔皮奥治疗有限公司 | 2021-01-08 | — | — | CN | claimed |
| CN-106554325-B | A kind of preparation method of chirality benzene sulfinyl aminated compounds | 上海交通大学 | 2019-02-22 | — | — | CN | claimed |
| CN-106554325-A | A kind of preparation method of chiral benzene sulfinyl aminated compounds | 上海交通大学 | 2017-04-05 | — | — | CN | claimed |
| EP-3107542-A1 | PROCESS FOR PREPARING N-BENZYL-3-HYDROXY-4-SUBSTITUTED-PYRIDIN-2-(1H)-ONES | Aerpio Therapeutics, Inc. (US) | 2016-12-28 | — | — | EP | claimed |
| CN-106232120-A | The method preparing N benzyl 3 hydroxyl 4 substituted pyridine 2 (1H) ketone | 爱尔皮奥治疗有限公司 | 2016-12-14 | — | — | CN | claimed |
| US-9388135-B2 | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2-(1H)-ones | AERPIO THERAPEUTICS, INC. (US) | 2016-07-12 | — | — | US | claimed |
| WO-2015126860-A1 | PROCESS FOR PREPARING N-BENZYL-3-HYDROXY-4-SUBSTITUTED-PYRIDIN-2-(1H)-ONES | AERPIO THERAPEUTICS, INC. (US) | 2015-08-27 | — | — | WO | claimed |
| US-20150232425-A1 | PROCESS FOR PREPARING N-BENZYL-3-HYDROXY-4-SUBSTITUTED-PYRIDIN-2-(1H)-ONES | AERPIO THERAPEUTICS, INC. | 2015-08-20 | — | — | US | claimed |
| CN-104447495-A | Preparation method of chiral beta-substituted-alpha, beta-unsaturated amino alcohol compound | UNIV SHANGHAI JIAOTONG | 2015-03-25 | — | — | CN | claimed |
| CN-117616032-A | Rare earth complex | 东曹株式会社 | 2024-02-27 | — | — | CN | disclosed |
| CN-110573013-B | Plant disease control agent | 明治制果药业株式会社 | 2021-10-29 | — | — | CN | disclosed |
| US-20210120817-A1 | PLANT DISEASE CONTROL AGENT | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2021-04-29 | — | — | US | disclosed |
| EP-3064997-B1 | LAMINATE AND USE OF A KIT FOR MANUFACTURING OF A LAMINATE | FUJIFILM CORP (JP) | 2021-04-28 | — | — | EP | disclosed |
| CN-110518284-B | Non-aqueous electrolyte, battery containing non-aqueous electrolyte and electric vehicle | 比亚迪股份有限公司 | 2021-04-20 | — | — | CN | disclosed |
| US-4599362-A | 2-aryl-ethyl ether derivatives and insecticidal and acaricidal agents containing said derivatives | MITSUITOATSU CHEMICALS, INC. (JP) | 1986-07-08 | — | — | US | disclosed |
| US-4570005-A | REACTING THE ARYL PROPYL CHLORIDE WITH THE CORRESPONDING ARYL ALCOHOL OR ARYL MERCAPTAN | MITSUITOATSU CHEMICALS INC. (JP) | 1986-02-11 | — | — | US | disclosed |
| US-4397864-A | LOW TOXICITY | MITSUITOATSU CHEMICALS INC. (JP) | 1983-08-09 | — | — | US | disclosed |
| US-4120886-A | APHIDICIDES | PPG INDUSTRIES, INC. (US) | 1978-10-17 | — | — | US | disclosed |
| US-4075006-A | PESTICIDES, NEMATOCIDES, FUNGICIDES | PPG INDUSTRIES, INC. (US) | 1978-02-21 | — | — | US | disclosed |
| US-4055656-A | S-ARYL-N-CYCLOALKYLTHIOLCARBAMATES | PPG INDUSTRIES, INC. (US) | 1977-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232425-A1 | PROCESS FOR PREPARING N-BENZYL-3-HYDROXY-4-SUBSTITUTED-PYRIDIN-2-(1H)-ONES | CYP4B1, CYP8B1, HPD | ACACB 3211/4885MAPT 3400/4885GPBAR1 4016/4885 |
| US-20210120817-A1 | PLANT DISEASE CONTROL AGENT | BROX, ALG1, CTRL | ACACB 896/4885MAPT 1126/4885GPBAR1 2399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.