Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 8/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28897940 | 0.85 | ALDH1A1 (0.42) | GPR88 | |
| SCHEMBL533652 | 0.83 | ACACB (0.37) | MCHR1MTNR1AMTNR1B | |
| SCHEMBL9988719 | 0.83 | ACACB (0.37) | MCHR1MTNR1AMTNR1B | |
| SCHEMBL1005061 | 0.82 | PPARG (0.30) | — | |
| SCHEMBL1454240 | 0.79 | MTNR1A (0.49) | MCHR1GPR88MTNR1AMTNR1B | |
| SCHEMBL28358697 | 0.78 | PPARG (0.32) | — | |
| SCHEMBL5273491 | 0.78 | MCHR1 (0.36) | MCHR1P2RX3GPR88MTNR1AMTNR1B | |
| SCHEMBL27566411 | 0.78 | P2RX3 (0.42) | MCHR1P2RX3SIGMAR1 | |
| SCHEMBL2088447 | 0.77 | ACACB (0.37) | MTNR1AMTNR1B | |
| SCHEMBL13657967 | 0.76 | GPR88 (0.40) | MCHR1GPR88SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1548020-B1 | SILICON COMPOUND | JNC CORP (JP) | 2014-07-23 | — | — | EP | disclosed |
| EP-1550664-B1 | SILICON COMPOUND | JNC CORP (JP) | 2012-06-27 | — | — | EP | disclosed |
| US-7964692-B2 | Polymer obtained by addition-polymerization initiated by a silicon compound | JNC CORPORATION (JP) | 2011-06-21 | — | — | US | disclosed |
| US-7863396-B2 | Silicon compounds | CHISSO CORPORATION (JP) | 2011-01-04 | — | — | US | disclosed |
| US-7662985-B2 | Polysilsesquioxanes; addition-condensation copolymers | CHISSO CORPORATION (JP) | 2010-02-16 | — | — | US | disclosed |
| EP-1650214-B1 | Silicon compound | CHISSO CORP (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-7563917-B2 | Silicon compound and a production process for silicon compound | CHISSO CORPORATION (JP) | 2009-07-21 | — | — | US | disclosed |
| US-20090143606-A1 | Production process for a silicon compound | JNC CORPORATION (JP) | 2009-06-04 | — | — | US | disclosed |
| US-20090137765-A1 | Polymer obtained by addition-polymerization initiated by a silicon compound | JNC CORPORATION (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-1686133-B1 | Organosilicon compound | CHISSO CORP (JP) | 2008-08-20 | — | — | EP | disclosed |
| US-20060094849-A1 | Silicon compound | JNC CORPORATION (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1650214-A2 | Silicon compound | CHISSO CORPORATION (JP) | 2006-04-26 | — | — | EP | disclosed |
| US-20050288468-A1 | Cyclic polysilsequisiloxanes substituted with a group containing a sulfonyl halide, especially ahalosulfonylphenyl group; living radical polymerization initiators, particularly for preparing acrylic polymers | JNC CORPORATION (JP) | 2005-12-29 | — | — | US | disclosed |
| US-20050250925-A1 | Silicon compound | JNC CORPORATION (JP) | 2005-11-10 | — | — | US | disclosed |
| EP-1550664-A1 | SILICON COMPOUND | CHISSO CORPORATION (JP) | 2005-07-06 | — | — | EP | disclosed |
| EP-1548020-A1 | SILICON COMPOUND | CHISSO CORPORATION (JP) | 2005-06-29 | — | — | EP | disclosed |
| US-20050033077-A1 | Production process for silicon compound and the same | JNC CORPORATION (JP) | 2005-02-10 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |
| US-4610804-A | Anthraquinone dyes and liquid crystal compositions including the same | HITACHI, LTD. (JP) | 1986-09-09 | — | — | US | disclosed |
| EP-0120463-A2 | Anthraquinone dyes and liquid crystal compositions including the same | HITACHI, LTD. (JP) | 1984-10-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143606-A1 | Production process for a silicon compound | NAF1, H1-0, SPTBN1 | MCHR1 1749/4885P2RX3 4508/4885GPR88 2761/4885 |
| US-20050288468-A1 | Cyclic polysilsequisiloxanes substituted with a group containing a sulfonyl halide, especially ahalosulfonylphenyl group; living radical polymerization initiators, particularly for preparing acrylic polymers | STS, SULT1A1, SRM | MCHR1 4194/4885P2RX3 1061/4885GPR88 2019/4885 |
| US-20050033077-A1 | Production process for silicon compound and the same | STS, SMS, SFXN1 | MCHR1 3283/4885P2RX3 2177/4885GPR88 1700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.