Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344138 | 0.89 | TMIGD3 (0.44) | CNR1CNR2KCNA3HPGDKDM4E | |
| SCHEMBL5341400 | 0.79 | DHODH (0.51) | HPGDKDM4EALDH1A1HSD17B10TMIGD3 | |
| SCHEMBL5337094 | 0.74 | ALDH1A1 (0.54) | CNR1HPGDKDM4EALDH1A1 | |
| SCHEMBL5337257 | 0.72 | ALDH1A1 (0.54) | CNR1HPGDKDM4EALDH1A1 | |
| SCHEMBL5343950 | 0.72 | NPC1 (0.53) | CNR1HPGDKDM4EALDH1A1 | |
| SCHEMBL5344215 | 0.68 | DHODH (0.56) | KDM4EALDH1A1TMIGD3 | |
| SCHEMBL5336574 | 0.67 | TP53 (0.48) | CNR1CNR2HPGDKDM4EALDH1A1 | |
| SCHEMBL5355542 | 0.67 | CNR1 (0.59) | CNR1CNR2HPGDKDM4EALDH1A1 | |
| SCHEMBL5337097 | 0.66 | SPTLC1 (0.53) | CNR1CNR2KCNA3HPGDKDM4E | |
| SCHEMBL10792063 | 0.66 | POLB (0.82) | HPGDKDM4EALDH1A1TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |