Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336571 | 0.89 | CNR1 (0.46) | TMIGD3CNR2KDM4EALDH1A1KCNA3 | |
| SCHEMBL5341400 | 0.82 | DHODH (0.51) | TMIGD3NR4A2NPC1KDM4EALDH1A1 | |
| SCHEMBL5344215 | 0.67 | DHODH (0.56) | TMIGD3NPC1KDM4EALDH1A1RAB9A | |
| SCHEMBL5339242 | 0.66 | ALDH1A1 (0.56) | TMIGD3NR4A2NPC1KDM4EALDH1A1 | |
| SCHEMBL5341342 | 0.66 | ALPL (0.49) | NPC1KDM4EALDH1A1RAB9APKM | |
| SCHEMBL5333968 | 0.66 | DHODH (0.79) | TMIGD3NPC1KDM4EALDH1A1RAB9A | |
| SCHEMBL5338077 | 0.65 | HTR4 (0.52) | CNR2NPC1KDM4EALDH1A1RAB9A | |
| SCHEMBL13381913 | 0.65 | HSD17B10 (0.49) | NPC1ALDH1A1LMNAHPGDCYP2C19 | |
| SCHEMBL5344142 | 0.64 | PDE4B (0.39) | CNR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8424856 | 0.63 | MEN1 (0.63) | KDM4EALDH1A1RAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |