Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336574 | 0.90 | TP53 (0.48) | PDE4BPDE4DCNR2TP53MDM2 | |
| SCHEMBL5341359 | 0.70 | NPC1 (0.51) | AURKA | |
| SCHEMBL17468714 | 0.69 | HPGD (0.52) | PDE4BPDE4APDE4DPDE4CCNR2 | |
| SCHEMBL5335055 | 0.68 | NAMPT (0.46) | HDAC6NAMPTHDAC1 | |
| SCHEMBL5337097 | 0.66 | SPTLC1 (0.53) | CNR2NAMPTTP53MDM2 | |
| SCHEMBL5337260 | 0.65 | CNR1 (0.56) | CNR2 | |
| SCHEMBL5343953 | 0.65 | CNR1 (0.57) | CNR2 | |
| SCHEMBL5318651 | 0.64 | HDAC1 (0.50) | CNR2HDAC6NAMPTTP53MDM2 | |
| SCHEMBL5344217 | 0.64 | LMNA (0.51) | TP53 | |
| SCHEMBL5344138 | 0.64 | TMIGD3 (0.44) | PDE4BPDE4APDE4DPDE4CCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |