SCHEMBL5336780

SCHEMBL5336780

CNc1ccnc(-c2ccccc2)c1C#N

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 16/20 0.55
ADORA2A P29274 5/20 0.55
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
ADORA2B P29275 4/20 0.49
HTT P42858 1/20 0.46
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5338881 0.83 ADORA1 (0.58) ADORA1ADORA2AMEN1KMT2AADORA2B
SCHEMBL7219981 0.76 ALDH1A1 (0.61) ADORA1ADORA2AMEN1KMT2A
SCHEMBL5329331 0.75 ADORA1 (0.56) ADORA1ADORA2AADORA2B
SCHEMBL18959392 0.73 BCL6 (0.49) HTTTSHR
SCHEMBL30608696 0.73 BCL6 (0.49) HTTTSHR
SCHEMBL3076234 0.72 SQOR (0.55) ADORA1ADORA2AMEN1KMT2AHTT
SCHEMBL19018356 0.71 ADORA1 (0.47) ADORA1ADORA2AMEN1KMT2AADORA2B
SCHEMBL2977679 0.71 ALDH1A1 (0.44) ADORA1ADORA2AMEN1KMT2A
SCHEMBL5336790 0.71 ALDH1A1 (0.73) ADORA1ADORA2AMEN1KMT2AADORA2B
Hydrochloric Acid SCHEMBL27958526 0.70 NTRK1 (0.46) ADORA1ADORA2AMEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007029062-A2 NOVEL PYRIDINE DERIVATIVES ORCHID RESEARCH LABORATORIES LIMITED (IN) 2007-03-15 WO claimed