Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5339653 | 0.80 | LMNA (0.39) | LMNAPOLBBRD9RAB9ARXFP1 | |
| SCHEMBL29931186 | 0.75 | GAA (0.41) | LMNAPOLBBRD9RAB9A | |
| SCHEMBL8886501 | 0.75 | HTT (0.43) | LMNAPOLBBRD9RAB9A | |
| SCHEMBL20315227 | 0.74 | RAB9A (0.45) | LMNAPOLBBRD9RAB9A | |
| SCHEMBL5339650 | 0.73 | PTPN11 (0.42) | NR1H4 | |
| SCHEMBL4848584 | 0.72 | TRPV1 (0.50) | — | |
| SCHEMBL14018973 | 0.72 | TRPV1 (0.50) | — | |
| SCHEMBL4848588 | 0.72 | TRPV1 (0.50) | — | |
| SCHEMBL3799518 | 0.71 | MAPT (0.33) | POLBRAB9A | |
| SCHEMBL17902833 | 0.71 | ALDH1A1 (0.47) | LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824468-A2 | GLYCOGEN SYNTHASE KINASE-3 INHIBITORS | Tel Aviv University Future Technology Development L.P. (IL) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006054298-A2 | GLYCOGEN SYNTHASE KINASE-3 INHIBITORS | TEL AVIV UNIVERSITY FUTURE TECHNOLOGY DEVELOPMENT L.P. (IL) | 2006-05-26 | — | — | WO | disclosed |