Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 4/20 | 0.50 |
| ▸ | SLC6A3 known ✓ | Q01959 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23527406 | 0.91 | SIGMAR1 (0.46) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL5086675 | 0.90 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL5093116 | 0.89 | SIGMAR1 (0.46) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL5085263 | 0.85 | BDKRB2 (0.48) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Bromide SCHEMBL5093241 | 0.84 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Iodide SCHEMBL5084931 | 0.84 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Bromide SCHEMBL5088337 | 0.84 | SIGMAR1 (0.46) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Iodide SCHEMBL5087175 | 0.84 | SIGMAR1 (0.46) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL11746968 | 0.83 | BDKRB2 (0.50) | SIGMAR1KCNH2TP53 | |
| Hydrochloric Acid SCHEMBL678119 | 0.83 | BDKRB2 (0.50) | SIGMAR1KCNH2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685702-B2 | Method for producing arene compounds and arene compounds produced by the same | JSI SILICONE CO. (KR) | 2023-06-27 | — | — | US | disclosed |
| US-20210188739-A1 | METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME | JSI SILICONE CO. (KR) | 2021-06-24 | — | — | US | disclosed |
| US-7235683-B2 | Organochlorosilane and dipodal silane compounds | GELEST INC. (US) | 2007-06-26 | — | — | US | disclosed |
| US-7235682-B2 | Process for manufacturing organochlorosilanes and dipodal silanes | GELEST INC. (US) | 2007-06-26 | — | — | US | disclosed |
| US-20070060765-A1 | ORGANOCHLOROSILANE AND DIPODAL SILANE COMPOUNDS | GELEST, INC. (US) | 2007-03-15 | — | — | US | disclosed |
| US-20050027138-A1 | Processes for manufacturing organochlorosilanes and dipodal silanes and silanes made thereby | GELEST INC. | 2005-02-03 | — | — | US | disclosed |
| US-20020082438-A1 | PROCESS FOR PREPARING ORGANOCHLOROSILANES BY DEHYDROHALOGENATIVE COUPLING REACTION OF ALKYL HALIDES WITH CHLOROSILANES | JUNG IL-NAM (KR) | 2002-06-27 | — | — | US | disclosed |
| US-6392077-B1 | DEHYDROHALOGENATION | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2002-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188739-A1 | METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME | PFAS, FRK, AGPAT2 | SLC6A2 4206/4885SLC6A3 3132/4885SIGMAR1 2580/4885 |
| US-20070060765-A1 | ORGANOCHLOROSILANE AND DIPODAL SILANE COMPOUNDS | DDT, PIK3C3, PKD1 | SLC6A2 3753/4885SLC6A3 2436/4885SIGMAR1 335/4885 |
| US-20050027138-A1 | Processes for manufacturing organochlorosilanes and dipodal silanes and silanes made thereby | DDT, PIK3C3, PIK3CD | SLC6A2 4135/4885SLC6A3 2590/4885SIGMAR1 333/4885 |
| US-20020082438-A1 | PROCESS FOR PREPARING ORGANOCHLOROSILANES BY DEHYDROHALOGENATIVE COUPLING REACTION OF ALKYL HALIDES WITH CHLOROSILANES | RCC1, RER1, RIF1 | SLC6A2 2591/4885SLC6A3 2426/4885SIGMAR1 152/4885 |
| US-11685702-B2 | Method for producing arene compounds and arene compounds produced by the same | PFAS, FRK, AGPAT2 | SLC6A2 4206/4885SLC6A3 3132/4885SIGMAR1 2580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.