Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.80 |
| ▸ | MAPT | P10636 | 4/20 | 0.80 |
| ▸ | HTT | P42858 | 2/20 | 0.78 |
| ▸ | RAB9A | P51151 | 2/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | LTA4H | P09960 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5659690 | 0.86 | ALDH1A1 (0.61) | ALDH1A1MAPTHTTRAB9ALMNA | |
| SCHEMBL3211268 | 0.85 | ALDH1A1 (0.69) | ALDH1A1MAPTHTTRAB9ALMNA | |
| Hydrochloric Acid SCHEMBL3210452 | 0.84 | ALDH1A1 (0.70) | ALDH1A1MAPTHTTRAB9ALMNA | |
| SCHEMBL27402246 | 0.83 | GAA (0.77) | ALDH1A1MAPTRAB9ALMNASMN1; SMN2 | |
| SCHEMBL5334244 | 0.83 | ALDH1A1 (0.97) | ALDH1A1MAPTRAB9ALMNASMN1; SMN2 | |
| SCHEMBL11147683 | 0.82 | ALDH1A1 (0.90) | ALDH1A1HTTRAB9ALMNASMN1; SMN2 | |
| SCHEMBL3040673 | 0.81 | LMNA (0.72) | ALDH1A1MAPTHTTRAB9ALMNA | |
| SCHEMBL10926918 | 0.81 | MEN1 (0.69) | ALDH1A1MAPTHTTRAB9ALMNA | |
| SCHEMBL13234930 | 0.81 | FAAH (0.70) | ALDH1A1MAPTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6795359 | 0.80 | ALDH1A1 (0.94) | ALDH1A1MAPTHTTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079003-A2 | AMIDE INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | claimed |
| WO-2007079003-A2 | AMIDE INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | disclosed |