Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056376 | 0.90 | PDE10A (0.46) | PDE10AALOX5APCYSLTR1CYSLTR2HTR2B | |
| SCHEMBL7801392 | 0.74 | MAPT (0.48) | ALOX5 | |
| SCHEMBL5333781 | 0.72 | PDE10A (0.40) | PDE10AALOX5APCYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL5334885 | 0.72 | GLA (0.39) | CYSLTR1CYSLTR2 | |
| SCHEMBL13765232 | 0.71 | PDE10A (0.39) | PDE10AALOX5APCYSLTR1CYSLTR2HTR2B | |
| SCHEMBL4052937 | 0.70 | MAPK14 (0.40) | PDE10AALOX5APCYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL7801372 | 0.70 | LTB4R (0.43) | PDE10AALOX5APCYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL10686237 | 0.68 | PDE10A (0.68) | PDE10ACYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9765540 | 0.67 | MEN1 (0.51) | — | |
| SCHEMBL8802103 | 0.66 | CYSLTR1 (0.64) | PDE10ACYSLTR1GPBAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309718-B2 | Dibenzocycloheptene compound | UBE INDUSTRIES, LTD. (JP) | 2007-12-18 | — | — | US | disclosed |
| US-20040180884-A1 | Dibenzocycloheptene compound | UBE INDUSTRIES, LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1408033-A1 | DIBENZOCYCLOHEPTENE COMPOUND | Ube Industries, Ltd. (JP) | 2004-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180884-A1 | Dibenzocycloheptene compound | LTB4R2, LTA4H, LTC4S | PDE10A 3445/4885ALOX5AP 80/4885CYSLTR1 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.