Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.39 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1941944 | 0.80 | ALDH1A1 (0.40) | CYP1A2HSD17B10ALDH1A1POLBCYP2C19 | |
| SCHEMBL114219 | 0.75 | ALDH1A1 (0.48) | CYP1A2HSD17B10ALDH1A1CYP2A6TSHR | |
| SCHEMBL7565940 | 0.74 | TRPM4 (0.38) | CYP1A2HSD17B10ALDH1A1CYP2A6TSHR | |
| SCHEMBL2145668 | 0.73 | — | — | |
| SCHEMBL5031460 | 0.73 | MCL1 (0.40) | CYP1A2HSD17B10TSHRTDP1HIF1A | |
| SCHEMBL5034793 | 0.73 | CYP1A2 (0.38) | CYP1A2HSD17B10ALDH1A1TSHRTDP1 | |
| SCHEMBL10877443 | 0.73 | CYP1A2 (0.43) | CYP1A2HSD17B10ALDH1A1CYP2A6TSHR | |
| SCHEMBL232693 | 0.71 | CYP2A6 (0.43) | CYP1A2HSD17B10ALDH1A1CYP2A6TSHR | |
| SCHEMBL232112 | 0.71 | CYP2A6 (0.46) | CYP1A2HSD17B10ALDH1A1CYP2A6TSHR | |
| SCHEMBL219753 | 0.71 | CYP2A6 (0.46) | CYP1A2HSD17B10ALDH1A1CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 492 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021081337-A1 | METHOD OF MODULATING RIBONUCLEOTIDE REDUCTASE | CASE WESTERN RESERVE UNIVERSITY (US) | 2021-04-29 | — | — | WO | claimed |
| EP-1836179-B1 | PIPERIDINE- AND PIPERAZINE-1-CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF FATTY ACID AMIDE HYDROLASE (FAAH) FOR THE TREATMENT OF ANXIETY, PAIN AND OTHER CONDITIONS | JANSSEN PHARMACEUTICA NV (BE) | 2015-05-06 | — | — | EP | claimed |
| US-8530476-B2 | Piperazinyl and piperidinyl ureas as modulators of fatty acid amide hydrolase | JANSSEN PHARMACEUTICA NV (BE) | 2013-09-10 | — | — | US | claimed |
| EP-2476681-A2 | Amino-aza-adamantane derivatives and methods of use | Abbott Laboratories (US) | 2012-07-18 | — | — | EP | claimed |
| US-20110118301-A1 | Amino-Aza-Adamantane Derivatives and Methods of Use | ABBOTT LABORATORIES (US) | 2011-05-19 | — | — | US | claimed |
| US-20110098309-A1 | METHODS OF INHIBITING THE FORMATION OF AMYLOID-BETA DIFFUSABLE LIGANDS USING ACYLHYDRAZIDE COMPOUNDS | ACUMEN PHARMACEUTICALS, INC. (US) | 2011-04-28 | — | — | US | claimed |
| US-20100292266-A1 | Oxazolyl Piperidine Modulators of Fatty Acid Amide Hydrolase | JANSSEN PHARMACEUTICA NV (BE) | 2010-11-18 | — | — | US | claimed |
| US-20100267784-A1 | NOVEL 4,5-DIHYDROISOXAZOLES WITH ESTROGENIC ACTIVITY | PULKKINEN JUHA | 2010-10-21 | — | — | US | claimed |
| EP-2194975-A2 | METHODS OF INHIBITING THE FORMATION OF AMYLOID-ß DIFFUSABLE LIGANDS USING A ACYLHYDRAZIDE COMPOUNDS | Acumen Pharmaceuticals, Inc. (US) | 2010-06-16 | — | — | EP | claimed |
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | BIOLIPOX AB | 2010-06-10 | — | — | US | claimed |
| EP-0210331-B1 | WATER SOLUBLE MONO AND DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-02-15 | — | — | EP | claimed |
| EP-0118881-B1 | BINDER-MIXTURES FOR OPTICAL RECORDING LAYERS AND ELEMENTS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-09-14 | — | — | EP | claimed |
| US-4703111-A | Water-soluble compounds containing one or two (nitrophenylamino)-phenylamino-chlorotriazinylamino groups, the nitrophenylamino being additionally substituted by a fiber-reactive group of the vinylsulfonyl series, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT A CORP. OF GERMANY (DE) | 1987-10-27 | — | — | US | claimed |
| EP-0127726-B1 | HYDROXAMIC ACIDS, THEIR PREPARATION AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS | VEB Fahlberg-List Magdeburg (DD) | 1987-08-26 | — | — | EP | claimed |
| US-4670469-A | ANTIASTHMATIC AGENTS; CARDIOVASCULAR DISORDERS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1987-06-02 | — | — | US | claimed |
| US-4626361-A | Binder-mixtures for optical recording layers and elements | EASTMAN KODAK COMPANY (US) | 1986-12-02 | — | — | US | claimed |
| US-4499165-A | COMPATABILITY; STABILITY; LASERS; DATA PROCESSING | EASTMAN KODAK COMPANY (US) | 1985-02-12 | — | — | US | claimed |
| EP-0127726-A1 | Hydroxamic acids, their preparation and their use in pharmaceutical compositions | VEB Fahlberg-List Magdeburg (DD) | 1984-12-12 | — | — | EP | claimed |
| EP-0118881-A2 | Binder-mixtures for optical recording layers and elements | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-09-19 | — | — | EP | claimed |
| US-3951944-A | Fiber-reactive, water-soluble disazo dyes containing an N-B-sulfoethylamide group | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267784-A1 | NOVEL 4,5-DIHYDROISOXAZOLES WITH ESTROGENIC ACTIVITY | ESR2, GPER1, CYP19A1 | CYP1A2 111/4885HSD17B10 183/4885ALDH1A1 622/4885 |
| US-20100292266-A1 | Oxazolyl Piperidine Modulators of Fatty Acid Amide Hydrolase | FAAH, FAAH2, APEH | CYP1A2 942/4885HSD17B10 762/4885ALDH1A1 635/4885 |
| US-20110098309-A1 | METHODS OF INHIBITING THE FORMATION OF AMYLOID-BETA DIFFUSABLE LIGANDS USING ACYLHYDRAZIDE COMPOUNDS | APP, APBA1, BACE1 | CYP1A2 3532/4885HSD17B10 2284/4885ALDH1A1 592/4885 |
| US-20110118301-A1 | Amino-Aza-Adamantane Derivatives and Methods of Use | CHRNA7, CHRNA5, CHRNA1 | CYP1A2 769/4885HSD17B10 2223/4885ALDH1A1 1034/4885 |
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | CYP1A2 146/4885HSD17B10 1149/4885ALDH1A1 1558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.