Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.55 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329633 | 0.79 | KMT2A (0.52) | KMT2ARAB9APDE10AMEN1 | |
| SCHEMBL5339343 | 0.72 | ICAM1 (0.42) | KDM4EALDH1A1MAPTTDP1LMNA | |
| SCHEMBL5332098 | 0.72 | MEN1 (0.49) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL27583319 | 0.72 | PDE5A (0.47) | TNFNOD1KDM4EALDH1A1MAPT | |
| SCHEMBL5330795 | 0.72 | IRAK4 (0.47) | KDM4EMAPTLMNAHPGDKMT2A | |
| SCHEMBL7404118 | 0.71 | TNF (1.00) | TNFNOD1KDM4EALDH1A1LMNA | |
| SCHEMBL5313426 | 0.70 | PTGS1 (0.46) | KDM4EALDH1A1MAPTTDP1HPGD | |
| SCHEMBL5333560 | 0.70 | MEN1 (0.55) | KDM4EALDH1A1MAPTTDP1LMNA | |
| SCHEMBL17127366 | 0.70 | ALDH1A1 (0.52) | KDM4EALDH1A1MAPTTDP1LMNA | |
| SCHEMBL27403244 | 0.69 | TNF (0.68) | TNFNOD1LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056214-A2 | N-ALKYL-N-ARYL-THIENOPYRIMIDIN-R-AMINES AND USES THEREOF | CYTOVIA, INC (US) | 2007-05-18 | — | — | WO | disclosed |